寿胎丸加味联合地屈孕酮治疗早期先兆流产合并SCH的临床研究

发布时间：2018-04-03 22:34

本文选题：寿胎丸加味　切入点：早期先兆流产　出处：《山东中医药大学》2017年硕士论文

【摘要】：目的:观察寿胎丸加味联合地屈孕酮治疗早期先兆流产合并绒毛膜下血肿(Subchorionic hematoma,SCH)的临床疗效,为更好的治疗早期先兆流产合并SCH提供新思路及临床依据。方法:纳入62例患者,均符合早期先兆流产合并SCH,中医证型为肾虚血热型的诊断标准。将纳入的患者随机分为试验组和对照组各31例,试验组给予寿胎丸加味联合地屈孕酮治疗,对照组给予地屈孕酮治疗,连续用药2周。观察两组SCH面积、SCH面积/孕囊面积以及中医证候积分的变化情况。结果:试验组的总有效率为90.32%,对照组总有效率67.74%,两者比较差异有统计学意义(P0.05);试验组在改善中医证候积分、减少阴道流血时间以及减小血肿方面均优于对照组,差异均具有统计学意义(P0.05)。治疗观察期间,试验组及对照组均未见不良反应。结论:寿胎丸加味联合地屈孕酮能够有效的改善早期先兆流产合并SCH患者的中医临床症状,减小SCH以及减少阴道流血时间。运用寿胎丸加味联合地屈孕酮治疗早期先兆流产合并SCH值得在临床上进一步应用与研究。
[Abstract]:Methods: 62 cases of early threatened abortion combined with SCH were included, and the TCM syndrome type was kidney deficiency and blood fever.The patients were randomly divided into trial group (n = 31) and control group (n = 31). The experimental group was treated with Shou-Feiwan plus Diproprogesterone, while the control group was treated with diproprogesterone for 2 weeks.The changes of SCH area / gestational sac area and TCM syndrome score were observed.Results: the total effective rate of the test group was 90.32 and the total effective rate of the control group was 67.74.The difference between the two groups was statistically significant (P 0.05), and the experimental group was superior to the control group in improving the score of TCM syndromes, reducing the vaginal bleeding time and reducing the hematoma.The difference was statistically significant (P 0.05).No adverse reactions were observed in both the experimental group and the control group during the treatment period.Conclusion: modified Shou-Tye Pill combined with Diproprogesterone can effectively improve the clinical symptoms of early threatened abortion with SCH, reduce SCH and reduce vaginal bleeding time.The treatment of early threatened abortion with SCH with modified Shou-Tye Pill and Diflexiplesterone is worthy of further clinical application and study.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R714.21

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