双胎妊娠产前筛查和产前诊断

发布时间：2018-04-08 12:07

本文选题：双胎妊娠　切入点：产前筛查　出处：《中国实用妇科与产科杂志》2015年09期

【摘要】：双胎妊娠的产前筛查和产前诊断与单胎比较其准确性差,咨询难度大。双胎妊娠的绒毛膜性诊断是双胎妊娠产前筛查的关键基础,目前不推荐对于双胎妊娠进行唐氏综合征的血清学筛查,而需要重视双胎妊娠早孕期的超声软指标筛查以及其他的结构筛查。无创产前筛查的方法对双胎妊娠有一定的筛查意义。高危孕妇采取介入性诊断技术进行染色体异常的检查时,对于单卵双胎妊娠建议进行1个胎儿的采样,而双卵双胎则需要分别采样,如为胎儿结构异常则无论其绒毛膜性均需要进行分别采样。双胎妊娠的介入性诊断流产率略高于单胎妊娠,手术前需要对孕妇及家属充分地知情告知。
[Abstract]:The accuracy of prenatal screening and prenatal diagnosis of twin pregnancy is lower than that of single pregnancy.The chorionic diagnosis of twin pregnancy is the key basis of prenatal screening of twin pregnancy. At present, it is not recommended to carry out serological screening for Down's syndrome in twin pregnancy.Attention should be paid to ultrasonic soft index screening and other structural screening during early pregnancy of twin pregnancy.The method of non-invasive prenatal screening has certain significance for screening twin pregnancy.When high-risk pregnant women use interventional diagnostic techniques to detect chromosome abnormalities, it is recommended that one fetus should be sampled for single egg twin pregnancy, and two egg twins should be sampled separately.If the fetal structure is abnormal, the chorionic villi need to be sampled separately.The interventional diagnosis abortion rate of twin pregnancy is slightly higher than that of single pregnancy. The pregnant women and their families should be informed before operation.
【作者单位】：北京大学第三医院妇产科;
【分类号】：R714.5

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