小剂量舒芬太尼预防剖宫产术中欣母沛不良反应的临床研究

发布时间：2018-04-11 23:23

本文选题：剖宫产 + 欣母沛　；参考：《实用妇产科杂志》2017年06期

【摘要】：目的:观察舒芬太尼用于防治剖宫产术中卡前列素氨丁三醇(欣母沛)引起不良反应的效果。方法:选择40例需要使用欣母沛的产妇,在连续硬膜外麻醉下行择期剖宫产术,随机分为舒芬太尼组和0.9%氯化钠组。舒芬太尼组在胎儿取出后应用欣母沛的同时,静脉注射舒芬太尼0.1μg/kg;0.9%氯化钠组在胎儿取出后应用欣母沛的同时,静脉注射同等剂量的0.9%氯化钠。监测两组产妇的平均动脉压(MAP)、心率(HR)、脉搏血氧饱和度(SpO_2)、呼吸频率(RR),观察宫体注射欣母沛后产妇恶心、呕吐、胸痛、腹痛、头晕头痛、面部潮红等不良反应,记录麻醉前、使用欣母沛30分钟及术毕的Ramsay镇静评分。结果:使用欣母沛30分钟后舒芬太尼组产妇MAP、HR及RR小于0.9%氯化钠组(P0.05),Ramsay镇静评分高于0.9%氯化钠组(P0.05);舒芬太尼组产妇恶心、胸腹痛、头晕头痛、面部潮红等发生率低于0.9%氯化钠组(P0.05)。结论:小剂量舒芬太尼可减少剖宫产术中欣母沛的不良反应,使循环更加平稳,且有一定的镇静效果,可安全有效用于临床。
[Abstract]:Aim: to observe the efficacy of sufentanil in preventing and treating adverse reactions caused by carprostin-aminotriol during cesarean section.Methods: 40 cases of parturient in need of Xinmupai were randomly divided into sufentanil group and 0.9% sodium chloride group after elective cesarean section under continuous epidural anesthesia.In sufentanil group, after fetuses were removed, the same dose of sodium chloride was given intravenously to sufentanil 0.1 渭 g 路kg ~ (-1) 路kg ~ (-9)% sodium chloride.The mean arterial pressure (MAPP), heart rate (HRG), pulse oxygen saturation (SPO _ 2) and respiratory frequency (RRN) were monitored in the two groups. The adverse reactions such as nausea, vomiting, chest pain, abdominal pain, dizziness and facial flushing were observed after intrauterine injection of Xinmupai, and the adverse reactions were recorded before anesthesia.Use Ramsay sedation score for 30 minutes and after operation.Results: after 30 minutes of use of Xinmu Pei, MAPHR and RR of puerpera in sufentanil group were lower than those in 0.9% sodium chloride group (P 0.05) and Ramsay sedation score were higher than 0.9% sodium chloride group (P 0.05), and the incidence of nausea, chest pain, dizziness and facial flushing in sufentanil group was lower than that in 0.9% sodium chloride group (P 0.05).Conclusion: low dose sufentanil can reduce the adverse reaction of Xinmupai during cesarean section, make circulation more stable, have certain sedative effect, and can be used safely and effectively in clinical practice.
【作者单位】：贵州医科大学附属医院麻醉科;
【分类号】：R719.8

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