女性高危型人乳头瘤病毒感染分布情况研究

发布时间：2018-04-13 06:44

本文选题：高危型人乳头瘤病毒 + 感染　；参考：《中国实用妇科与产科杂志》2017年01期

【摘要】：目的探讨浙江省富阳地区女性高危型人乳头瘤病毒(HPV)感染率和基因型分布情况。方法采用荧光PCR法,对2013年4月至2015年11月富阳区第一人民医院和富阳区妇幼保健院妇科就诊的13 447例患者宫颈标本检测世界卫生组织(WHO)确认的13种高危HPV型别,包括HPVl6、18、31、33、35、39、45、51、52、56、58、59和68型。结果高危型HPV基因检测感染率为24.57%(3304/13 447),其中单一基因型感染率为17.97%(2416/13 447),多重亚型混合感染率为6.60%(888/13 447);其中以HPV52、HPV16、HPV58三种亚型最多见,所占比例分别为6.51%、5.87%、4.47%。结论浙江省富阳地区妇科就诊女性患者HPV感染以HPV52、HPV16、HPV58三型较多见,常见感染亚型总体符合亚洲国家分布情况,同时又具有其独特的地区分布特点。
[Abstract]:Objective to investigate the female high-risk human papilloma virus in Zhejiang area of Fuyang province (HPV) infection rate and genotype distribution. Using fluorescence PCR detection method, 13447 cases of patients with cervical specimens of WHO on maternal and Child Health Hospital of the first people's Hospital from April 2013 to November 2015 in Fuyang district and Fuyang District gynecology clinic (WHO) 13 high-risk HPV type confirmation, including HPVl6,18,31,33,35,39,45,51,52,56,58,59 and type 68. The detection of high-risk type HPV gene infection rate was 24.57% (3304/13 447), in which a single genotype infection rate was 17.97% (2416/13 447), multiple subtypes of mixed infection rate was 6.60% (888/13 447); the HPV52, HPV16, HPV58 three subtypes of the most common the proportion was 6.51%, 5.87%, 4.47%. HPV conclusion patients with gynecological clinic women in Fuyang area of Zhejiang province with HPV52 infection, HPV16, HPV58 three were more common, common subtype infection generally conforms to the Asian The distribution of the country, at the same time has its unique regional distribution characteristics.

【作者单位】：富阳区第一人民医院;富阳区妇幼保健院;
【基金】：杭州市科技发展计划项目(NO.20130733Q49)
【分类号】：R737.33

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