基于QLICP-OV量表的卵巢癌患者生命质量及其与临床客观指标的典型相关分析

发布时间：2018-04-14 08:16

本文选题：卵巢癌 + 生命质量　；参考：《现代预防医学》2017年01期

【摘要】：目的探讨卵巢癌患者生命质量状况及其与临床客观指标的关系。方法应用卵巢癌QLICP-OV(V2.0)量表对118例卵巢癌患者进行调查,同时收集患者临床客观指标资料,并采用典型相关分析客观指标与生命质量的关系。结果卵巢癌患者的总体生命质量得分(69.59±10.24)分,躯体功能领域(62.37±14.75)分,心理功能领域(64.50±15.19)分,社会功能领域(67.06±15.83)分,共性症状与副作用领域(72.19±16.78)分,特异模块领域(80.17±15.84)分。典型相关分析得到三对有统计学意义的典型变量,典型相关系数分别为0.60、0.47、0.46(P1、P2、P30.05),三对典型变量可解释83.7%的信息量。结论卵巢癌患者生命质量与临床客观指标间存在一定的相关性。可进一步分析二者间存在相关的原因,为提高卵巢癌患者生命质量提供依据。
[Abstract]:Objective to investigate the quality of life (QOL) in patients with ovarian cancer and its relationship with clinical objective indexes.Methods 118 patients with ovarian cancer were investigated with QLICP-OV2.0 scale, and objective clinical data were collected, and the relationship between objective indexes and quality of life was analyzed by canonical correlation analysis.Results the total quality of life (QOL) score was 69.59 卤10.24 in patients with ovarian cancer, 62.37 卤14.75 in physical function, 64.50 卤15.19 in psychological function, 67.06 卤15.83 in social function, 72.19 卤16.78 in common symptom and side effect, 80.17 卤15.84 in specific module.Three pairs of typical variables with statistical significance were obtained by canonical correlation analysis. The canonical correlation coefficients were 0.60 ~ 0.47 ~ 0.46 ~ 0.46 / P _ (1) P _ (2) P _ (30.05) and 83.7% of the information content could be explained by three pairs of typical variables.Conclusion there is a certain correlation between quality of life and clinical objective indexes in ovarian cancer patients.It is possible to further analyze the causes of correlation between the two and provide evidence for improving the quality of life of patients with ovarian cancer.
【作者单位】：广东医科大学公共卫生学院;云南省肿瘤医院妇瘤科;广东医科大学附属医院;湛江肿瘤医院;
【基金】：国家自然科学基金(81302510,81273185) 广东省医学科研基金(A2012423)资助
【分类号】：R737.31

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