女性盆腔浆液性癌20例临床病理分析
发布时间:2018-04-14 13:09
本文选题:盆腔肿瘤 + 浆液性癌 ; 参考:《临床与实验病理学杂志》2015年03期
【摘要】:目的探讨女性盆腔浆液性癌(pelvic serous carcinoma,PSC)的临床病理学特征、免疫表型、发病机制及鉴别诊断。方法回顾性分析20例PSC的临床病理资料、组织学形态及免疫表型,并复习相关文献。结果 20例PSC,年龄23~87岁,平均58.9岁。PSC可发生于输卵管、卵巢和腹膜,常因腹胀、腹痛或盆腔占位就诊,发现时常广泛累及盆腔多个脏器,不易明确原发部位。输卵管浆液性癌原发灶小,易种植,卵巢和腹膜浆液性癌常伴有浆液性输卵管上皮内癌(serous tubal intraepithelial carcinoma,STIC)。结论输卵管黏膜上皮细胞可能是PSC的主要来源。诊断PSC时需仔细检查输卵管以明确其原发部位,病变广泛累及腹膜时需与腹膜间皮瘤和盆腔外腺癌腹膜转移相鉴别。
[Abstract]:Objective to investigate the clinicopathological features, immunophenotype, pathogenesis and differential diagnosis of female pelvic serous carcinoma (serous).Methods the clinicopathological data, histological morphology and immunophenotype of 20 cases of PSC were analyzed retrospectively.Results 20 cases of PSC-23 ~ 87 years old, mean 58.9 years old. PSC can occur in oviduct, ovary and peritoneum, often due to abdominal distension, abdominal pain or pelvic space occupying. It is often found that multiple organs of pelvic cavity are frequently involved and it is difficult to identify the primary location.Serous carcinoma of fallopian tube is small and easy to implant. Ovarian and peritoneal serous carcinoma is often accompanied by serous tubal intraepithelial carcinoma.Conclusion the epithelial cells of fallopian tube mucosa may be the main source of PSC.In the diagnosis of PSC, the fallopian tubes should be carefully examined to identify the primary location, and peritoneal metastases should be distinguished from peritoneal mesothelioma and extrapelvic adenocarcinoma when the lesions are extensively involved in the peritoneum.
【作者单位】: 首都医科大学石景山教学医院/北京市石景山医院病理科;
【分类号】:R737.3
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