广东省HIV感染母亲所生新生儿低出生体重的影响因素分析

发布时间：2018-04-14 18:37

本文选题：艾滋病病毒感染母亲 + 低出生体重　；参考：《中国艾滋病性病》2017年10期

【摘要】：目的分析广东省艾滋病病毒(HIV)感染母亲所生新生儿,发生低出生体重的影响因素。方法提取2007年1月至2015年6月,广东省免费预防艾滋病母婴传播项目登记的1 365例HIV感染母亲及其所生活产新生儿的个案调查数据,采用多因素Logistic回归分析。结果HIV感染母亲所生的1 365名新生儿中,13.11%(179人)的出生体重2 500g(低出生体重),1.03%(14例)的出生体重1 500g(极低出生体重)。这些新生儿低出生体重的高危因素有母亲年龄较大[矫正比值比(aOR)=1.05,95%可信区间(CI):1.02~1.08]、流动人口[市内各县区间流动(aOR=1.77,95%CI:1.14~2.75)、省内各市间流动(aOR=2.52,95%CI:1.41~4.48)]、注射吸毒感染HIV(aOR=2.53,95%CI:1.09~5.91)、围产期发生并发症(aOR=2.52,95%CI:1.68~3.79)、孕期服用抗艾滋病病毒药物(aOR=1.84,95%CI:1.24~2.71)、早产[28-32周(aOR=58.01,95%CI:7.07~476.04),33-36周(aOR=4.64,95%CI:2.34~9.21)]、以及女性新生儿(aOR=1.72,95%CI:1.18~2.51)。结论 HIV感染母亲所生新生儿低出生体重的发生受母亲社会经济特征、围产期高危因素和新生儿性别等多因素影响,需要综合评估和干预。
[Abstract]:Objective to analyze the influencing factors of low birth weight in newborns born to mothers infected with HIV / AIDS in Guangdong province.Methods from January 2007 to June 2015, 1 365 cases of mothers with HIV infection and their newborns were collected from Guangdong Province. The data were analyzed by multivariate Logistic regression analysis.Results the birth weight of 1 365 newborns born to mothers with HIV infection was 2 500 g (low birth weight 1.03%), and the birth weight was 1 500 g (very low birth weight).The high risk factors for these newborns with low birth weight are older mothers [corrected ratio is 1.0595% CI: 1.02U 1.08], floating population [1.77-95% CI: 1.14C 1.75%, flow between cities and cities in the province], injecting drug use and infection with HIVA ORA OR 2.539 95 CI1.09.91%, perinatal period occurs in the perinatal period.Conclusion the incidence of low birth weight of newborns born to mothers with HIV infection is affected by many factors, such as the social and economic characteristics of mothers, perinatal high risk factors and sex of newborns, etc. It needs comprehensive evaluation and intervention.
【作者单位】：广东省妇幼保健院;
【基金】：广东省省级科技计划项目(2014A020212245)~~
【分类号】：R714.251

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