低分子肝素钠治疗复发性流产对前置胎盘及早产的影响

发布时间：2018-04-19 19:20

本文选题：复发性流产 + 低分子肝素钠　；参考：《实用妇产科杂志》2017年06期

【摘要】：目的:探讨低分子肝素钠治疗复发性流产对前置胎盘及早产的影响。方法:回顾性分析2015年1月至2016年1月就诊我院并分娩的孕妇中,符合纳入及排除标准的50例有复发性流产史的孕妇,予以低分子肝素钠治疗为治疗组,既往有复发性流产史,未予低分子肝素钠治疗的孕妇50例为对照组,随机选取同期我院正常分娩的孕妇200例为正常组。对照组给予常规保胎治疗,治疗组在对照组的基础上给予低分子肝素钠治疗;比较3组病例前置胎盘、产后出血及早产发生率。结果:对照组前置胎盘发生率(30%)明显高于治疗组(12%),两者比较差异有统计学意义(P0.05);治疗组早产发生率(0)明显低于对照组(14%),差异有统计学意义(P0.05);对照组前置胎盘、产后出血及早产发生率均高于正常组,差异有统计学意义(P0.05)。结论:复发性流产患者前置胎盘、产后出血及早产发生率比正常妊娠孕妇高,应用低分子肝素钠有可能降低复发性流产患者前置胎盘和早产的发生率。
[Abstract]:Objective: to investigate the effect of low molecular weight heparin sodium (LMWH) on placenta previa and premature delivery in recurrent abortion. Methods: from January 2015 to January 2016, 50 pregnant women who met the criteria of inclusion and exclusion were treated with low molecular weight heparin sodium (LMWH) as treatment group. 50 pregnant women who were not treated with low molecular weight heparin sodium as control group and 200 pregnant women in the same period of normal delivery were randomly selected as normal group. The patients in the control group were treated with low-molecular-weight heparin sodium on the basis of the control group, and the incidence of placenta previa, postpartum hemorrhage and premature delivery were compared among the three groups. Results: the incidence of placenta previa in the control group was significantly higher than that in the treatment group (P 0.05), and the incidence of premature delivery in the treatment group was significantly lower than that in the control group (P 0.05), and the placenta previa in the control group was significantly lower than that in the control group (P 0.05). The incidence of postpartum hemorrhage and premature delivery was higher than that of normal group (P 0.05). Conclusion: the incidence of placenta previa, postpartum hemorrhage and preterm delivery in patients with recurrent abortion is higher than that in normal pregnant women. Low molecular weight heparin sodium may reduce the incidence of placenta previa and preterm delivery in patients with recurrent abortion.
【作者单位】：贵州医科大学附属医院;
【基金】：贵阳市科技计划项目(编号:20161001)
【分类号】：R714.21

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