卵巢动脉血流指数对体外受精-胚胎移植患者妊娠结局的影响

发布时间：2018-04-22 03:00

本文选题：体外受精-胚胎移植 + 卵巢动脉　；参考：《实用医学杂志》2017年07期

【摘要】：目的:探讨卵巢动脉血流指数对体外受精-胚胎移植患者妊娠结局的影响。方法:选取2014年2月至2016年4月进行体外受精-胚胎移植的不孕患者136例为研究对象,根据是否妊娠分为妊娠组与未妊娠组,经阴道B超对两组患者人绒毛促性腺激素(HCG)日和月经第2天(M2)的卵巢动脉血流阻力指数(RI)、搏动指数(PI)及其动脉舒张压血流速度高低比值(S/D)进行监测。并对两组血流指数的差异进行分析。结果:与未妊娠组对比,妊娠组患者M2日RI、PI及S/D降低,差异有统计学意义(P0.05),HCG日RI、PI也显著降低,差异有统计学意义(P0.05),S/D无明显变化,差异无统计学意义(P0.05)。与同组M2日对比,妊娠组患者HCG日RI及PI均明显降低,未妊娠组患者HCG日RI及PI也明显降低,差异有统计学意义(P0.05),S/D对比无差异(P0.05)。结论:卵巢动脉血流RI及PI与卵巢储备功能存在密切联系,是预测体外受精-胚胎移植结局的有效指标,能够为体外受精-胚胎移植技术的前期准备及治疗提供更科学的依据。
[Abstract]:Objective: to investigate the effect of ovarian artery blood flow index on pregnancy outcome in IVF-embryo transfer patients. Methods: 136 infertile patients undergoing in vitro fertilization and embryo transfer from February 2014 to April 2016 were selected and divided into pregnancy group and non-pregnancy group according to whether they were pregnant or not. The ovarian artery resistance index (RI), pulsatile index (Pi) and the ratio of diastolic blood flow velocity (DBP) and the ratio of blood flow velocity (S / D) of the two groups were monitored by transvaginal ultrasonography on the day of HCG (human chorionic gonadotropin) and the second day of menstruation. The difference of blood flow index between the two groups was analyzed. Results: compared with the non-pregnant group, the RIP and S / D in the M 2 group were significantly lower than those in the non-pregnant group, and the difference was statistically significant (P 0.05). There was no significant difference between the two groups (P 0.05 / D), and there was no significant difference between the two groups (P 0.05). Compared with the same group, the RI and Pi of HCG in pregnancy group were significantly lower than those in the same group, and the RI and Pi of HCG day in non-pregnancy group were significantly lower than those in the same group. There was no significant difference in P 0.05 / S / D comparison between pregnancy group and non-pregnancy group. Conclusion: there is a close relationship between RI and Pi of ovarian artery blood flow and ovarian reserve function, which is an effective index to predict the outcome of in vitro fertilization and embryo transfer, and can provide a more scientific basis for the preparation and treatment of in vitro fertilization and embryo transfer.
【作者单位】：安徽医科大学第一附属医院生殖医学中心;妇幼保健院;
【分类号】：R714.8

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