阿奇霉素与寨卡病毒

发布时间：2018-04-22 10:08

本文选题：神经胶质细胞 + 小头　；参考：《中国感染与化疗杂志》2017年06期

【摘要】：正对许多原发性小头症进行病理学检查显示,无炎性改变,无坏死。这与胎儿大脑感染寨卡病毒引起小头症的研究结果不同。在胎儿大脑感染中,小头畸形伴随着小神经胶质细胞的激活,弥漫性神经胶质增生、坏死,脑室周围和皮质钙化,以及大脑收缩产生的脑积水。原发性小头症可能是由于缺乏放射状神经胶质(radial glia)的神经干细胞所致。Retallack及其同事发现编码黄病毒进入细胞的多个基因在放射状神经胶质细胞、星形细胞、内皮细胞和小神经
[Abstract]:Pathological examination of many primary microcephaly showed no inflammatory changes and no necrosis. This is different from the study of microcephaly caused by Zika virus infection in the fetal brain. In fetal brain infection, microcephaly is associated with activation of microglia, diffuse glial hyperplasia, necrosis, periventricular and cortical calcification, and hydrocephalus caused by brain contraction. Primary microcephaly may be caused by a lack of radial glial neural stem cells. Retallack and his colleagues found that multiple genes encoding the yellow virus enter the cells in the radial glia, astrocytes, endothelial cells and small nerves
【分类号】：R714.5

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