六氟化硫微泡在HIFU治疗T2WI高信号子宫肌瘤中的临床应用

发布时间：2018-05-02 22:13

  本文选题：子宫肌瘤 + 超声消融　； 参考：《昆明医科大学学报》2016年11期

【摘要】：目的探讨六氟化硫微泡在高强度聚焦超声治疗T2高信号子宫肌瘤中的应用价值.方法选取昆明医科大学第一附属医院36例单发T2高信号子宫肌瘤患者随机分成研究组和对照组,对照组18例患者术中不用六氟化硫微泡,研究组18例患者术中使用六氟化硫微泡.分别记录2组的手术时间(min)、出现块状灰度变化时间(s)、辐照时间(s)、治疗剂量(J),并发症发生的情况及消融率(%).结果研究组手术时间、出现块状灰度变化时间(s)、辐照时间(s)、治疗剂量分别为(101.51±43.02)min,(856.42±451.14)s,(1077.37±546.23)s,(496 581.81±267 192.31)J,对照组分别为(261.34±85.53)min,(1 833.32±642.67)s,(1 890.21±1 268.43)s,(784 608.31±357 621.45)J,2组各参数相比差异有统计学意义(P0.05).研究组消融率为83.3%,对照组消融率为55.5%,2组参数相比差异有统计学意义(P0.05).研究组患者出现全身麻木1例,没有发生治疗区皮肤烧伤.对照组治疗区皮肤Ⅱ°烧伤1例,全身麻木2例,并发症的发生率为1/18(5.5%),2组均未出现肠穿孔、膀胱穿孔等严重并发症.结论六氟化硫微泡在高强度聚焦超声热消融T2高信号子宫肌瘤中可缩短手术时间,减少并发症,提高消融率,在临床中发挥着重要的应用价值.
[Abstract]:Objective to evaluate the value of sulfur hexafluoride microbubbles in the treatment of T 2 hysteromyoma with high intensity focused ultrasound (HIFU). Methods Thirty-six patients with single T2 hyperintense hysteromyoma were randomly divided into two groups: the control group (n = 18) and the control group (n = 18). In the study group, 18 patients were treated with sulfur hexafluoride microbubbles during operation. The operation time, time of massive gray scale change, irradiation time, therapeutic dose, complications and ablation rate were recorded in the two groups. Results in the study group, the operation time, the time of massive gray scale change and the irradiation time were 101.51 卤43.02min, 856.42 卤451.14min, 1077.37 卤546.23, 496 卤581.81 卤262.31 and 261.34 卤85.53min respectively. There were significant differences between the two groups (P 0.05). The ablation rate was 83.3 in the study group and 55.5 in the control group. One case of systemic numbness occurred in the study group, and no skin burn occurred in the treatment area. In the control group, there were 1 case of skin 鈪，

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