盆底型子宫内膜异位症患者行IVF-ET助孕后妊娠结局及妊娠期并发症的分析

发布时间：2018-05-06 05:40

本文选题：体外受精-胚胎移植(IVF-ET) + 盆底型子宫内膜异位症(EMs)　；参考：《生殖与避孕》2015年08期

【摘要】：目的:探讨盆底型子宫内膜异位症(EMs)患者行IVF-ET助孕后妊娠结局及妊娠期并发症。方法:回顾性分析行IVF-ET治疗获临床妊娠的盆底型EMs 96个周期(A组),卵巢子宫内膜异位囊肿者107个周期(B组),并选择同期180个周期输卵管因素行IVF-ET助孕获临床妊娠者为对照组(C组)。分析比较各组患者行IVF-ET助孕的妊娠结局及妊娠期并发症。结果:A组早产率显著低于B组(9.38%vs 21.50%,P0.05);流产率(25.00%vs 12.78%)及单胎流产率(35.00%vs 17.31%)明显高于C组,差异有统计学意义(P0.05);异位妊娠发生率略高于B组(2.08%vs 1.87%),低于C组(6.67%),但3组间无统计学差异(P=0.072)。A组和B组妊娠期并发症发生率明显高于C组(30.21%vs 31.78%vs 16.11%,P0.05),但A、B组间无统计学差异(P0.05)。其中A组和B组子痫前期(8.33%vs 9.35%)、前置胎盘(9.38%vs 10.28%)发生率显著高于C组(2.78%;3.33%);A组先兆流产率高于B组和C组(18.75%vs 14.02%vs 8.33%),且与C组差异有统计学意义(P0.05)。结论:盆底型EMs患者行IVF-ET助孕其自然流产率显著高于输卵管不孕患者,早产率较卵巢型EMs降低;妊娠期并发症较输卵管不孕患者明显增多,主要表现在子痫前期、前置胎盘及先兆流产3个方面,而与卵巢型EMs无统计学差异。
[Abstract]:Objective: to investigate the pregnancy outcome and pregnancy complications after IVF-ET in patients with pelvic floor endometriosis. Methods: retrospective analysis of IVF-ET treatment of pelvic floor type EMs 96 cycles group A, ovarian endometriosis cysts 107 cycles of group B, and the selection of 180 oviduct factors in the same period to help pregnancy clinical pregnancy with IVF-ET Group C: control group. The pregnancy outcome and pregnancy complications were analyzed and compared in each group with IVF-ET. Results the premature delivery rate in group A was significantly lower than that in group B (9.38 vs 21.50P0.05; the abortion rate was 25.00 vs 12.78) and the rate of single child abortion was 35.00 vs 17.31). The incidence of ectopic pregnancy was slightly higher in group B than in group B (2.08 vs 1.87) and lower than that in group C (6.67%), but there was no significant difference among the three groups in the incidence of pregnancy complications in group A and group B, which were significantly higher than those in group C (30.21 vs 31.78%vs 16.11, P 0.05), but there was no significant difference between group B and group B (P 0.05). The incidence of preeclampsia in group A and group B was higher than that in group C (8.33 vs 9.35 and 9.38 vs 10.28). The rate of threatened abortion in group A was higher than that in group B and group C (18.75 vs 14.02%vs 8.33), and there was a significant difference between group A and group C (P 0.05). Conclusion: the spontaneous abortion rate of pelvic floor type EMs patients with IVF-ET assisted pregnancy is significantly higher than that of oviductal infertility patients, and the premature delivery rate is lower than that of ovarian type EMs, and the complications of pregnancy are more than that of oviduct infertility patients, mainly in preeclampsia. Placenta previa and threatened abortion had no statistical difference with ovarian type EMs.
【作者单位】：安徽医科大学第一附属医院生殖医学中心;
【分类号】：R714.8

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