复方益母草口服液联合缩宫素预防阴道分娩产妇产后出血及促进子宫复旧的效果与安全性

发布时间：2018-05-06 22:22

本文选题：复方益母草口服液 + 缩宫素　；参考：《中国药房》2015年33期

【摘要】：目的:观察复方益母草口服液联合缩宫素预防阴道分娩产妇产后出血及促进子宫复旧的效果与安全性。方法:240例经产道自然分娩的产妇随机均分为对照组和观察组。对照组产妇分娩后,臀部立即注射缩宫素20 U。观察组患者在对照组的基础上加服复方益母草口服液20 ml,每日3次,连续服用两周。观察两组产妇产后阴道出血、子宫复旧及不良反应发生情况。结果:观察组产妇产后1 h出血量、1~2 h出血量、产后42 d复查时宫底高度与对照组比较,差异均无统计学意义(P0.05);观察组产妇产后2~24 h出血量、产后出血的发生率,产后42 d复查时子宫体大小、宫腔积血情况、恶露持续时间均显著优于对照组,差异均具有统计学意义(P0.05)。两组产妇均未见发热、皮疹、恶心等明显药物不良反应发生。结论:复方益母草口服液联合缩宫素能明显减少阴道分娩产妇产后出血、促进子宫复旧,且安全性较好。
[Abstract]:Objective: to observe the effect and safety of compound Leonurus oral liquid combined with oxytocin in preventing postpartum hemorrhage and promoting uterine restoration. Methods 240 cases of parturient delivered by birth canal were randomly divided into two groups: control group and observation group. In the control group, oxytocin 20 U was injected into the buttocks immediately after parturition. The patients in the observation group were given 20 ml of compound Leonurus oral liquid three times a day for two weeks on the basis of the control group. To observe the occurrence of postpartum vaginal hemorrhage, uterine retrogression and adverse reactions in the two groups. Results: there was no significant difference between the observation group and the control group in the volume of blood loss at 1 hour and 2 hours after delivery, the height of the fundus of uterus was not significantly different from that in the control group at 42 days postpartum, the amount of blood lost at 24 hours after parturition and the incidence of postpartum hemorrhage in the observation group were not significantly different from those in the control group. At 42 days postpartum, the uterine body size, uterine cavity hemorrhage and lochia duration were significantly better than those in the control group, and the difference was statistically significant (P 0.05). Fever, rash, nausea and other adverse drug reactions were not found in both groups. Conclusion: compound Leonurus oral liquid combined with oxytocin can significantly reduce postpartum hemorrhage, promote uterine restoration and improve the safety of vaginal delivery.
【作者单位】：唐山市妇幼保健院药剂科;唐山市妇幼保健院妇产科;
【分类号】：R714.3

【参考文献】