单通道与腔内结合插植后装治疗宫颈癌的剂量比较

发布时间：2018-05-10 15:54

本文选题：宫颈癌 + 后装放疗　；参考：《广东医学》2015年05期

【摘要】：目的比较腔内结合插植后装(IC/IS BT)与单通道后装(IC BT)治疗宫颈癌的剂量学差异,明确IC/IS BT在宫颈癌放疗中的价值。方法选取宫颈癌患者26例,行宫腔置管加两侧宫颈插植,模拟IC BT及IC/IS BT在靶区剂量、危及器官受量、剂量分布均匀性与适形性等比较。结果在给予A点相同处方剂量的情况下,IC BT的靶区剂量(D90、D100)显著高于IC/IS BT(P0.001),而两者间高剂量体积分数(V150、V200)的差异无统计学意义(P0.05);IC/IS BT的各危及器官的D2cc、D1cc、D0.1cc均显著小于IC BT(P0.001)。IC/IS BT在覆盖指数、适形指数、剂量均匀指数显著优于IC BT,显示出更适形的靶区覆盖和更均匀的剂量分布(P0.001)。结论IC/IS BT在保护周围危及器官和提高剂量分布适形性和均匀性方面与IC BT比较具有明显的优势,值得推广。
[Abstract]:Objective to compare the dosimetric differences between intracavitary and implanted IC-IS BTs and single-channel afterloading IC BTTs in the treatment of cervical cancer, and to determine the value of IC/IS BT in the radiotherapy of cervical cancer. Methods 26 patients with cervical cancer were treated with intrauterine catheterization and bilateral cervical implantation. The dose of ICBT and IC/IS BT in target area was simulated, and the dose distribution uniformity and conformability were compared. Results under the condition of the same prescription dose of point A, the target dose of ICBT was significantly higher than that of IC/IS BTBT P0.001g, but there was no significant difference between the two groups in high dose volume fraction (V150 / V200). The D2ccD1ccD0.1cc of each organ endangered by ICP-ISBT was significantly lower than that of IC-BT in coverage index. The conformal index and dosimetric uniformity index were significantly better than that of IC BT.The results showed that the target coverage and the dose distribution were more suitable and uniform (P 0.001). Conclusion IC/IS BT has obvious advantages over IC BT in protecting the surrounding organs and improving the conformability and uniformity of dose distribution, which is worth popularizing.
【作者单位】：中山大学肿瘤防治中心、华南肿瘤学国家重点实验室放疗科;
【分类号】：R737.33

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