围孕期补充叶酸对不良妊娠结局的影响

发布时间：2018-05-12 21:47

本文选题：叶酸 + 妊娠期女性　；参考：《中国实用妇科与产科杂志》2017年11期

【摘要】：正叶酸(FA)最初被认为可以治疗贫血而进入临床使用,随后发现,孕早期补充叶酸可以有效降低胚胎神经管畸形(NTDs)、子痫前期等妊娠期并发症的发生率。本文综述了孕期女性叶酸的补充与不良妊娠结局的相关研究进展。1中国孕妇叶酸缺乏较为普遍妊娠期是机体急需补充叶酸的特殊生理时期。WHO建议,所有女性从准备妊娠应开始每日额外补充叶酸400μg,至少维持至妊娠12周。而当胎儿诊断为神经管缺陷或前期出现过神经管缺
[Abstract]:It was found that folic acid supplementation in early pregnancy can effectively reduce the incidence of complications during pregnancy, such as NTDsn, preeclampsia and so on. This paper reviews the research progress of folic acid supplementation and adverse pregnancy outcome in pregnant women. The general pregnant period of folic acid deficiency in pregnant women in China is a special physiological period for the body to be in urgent need of folic acid supplementation. All women should begin daily supplementation of folic acid 400 渭 g daily from pregnancy preparation until at least 12 weeks gestation. And when the fetus is diagnosed with a neural tube defect or there has been a neural tube defect in the early stages,
【作者单位】：广州医科大学附属第三医院妇产科广东省产科重大疾病重点实验室;
【基金】：国家重点研发计划资助(2016YFC1000405) 国家自然科学基金面上项目(81370775、81571518) 广东省教育厅项目(2015KCXTD020)
【分类号】：R714.2

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