脉冲多普勒取样容积位置对胎儿肺动脉血流频谱参数影响的研究

发布时间：2018-05-24 23:20

本文选题：胎儿 + 肺动脉　；参考：《中国超声医学杂志》2017年10期

【摘要】：目的通过将脉冲多普勒取样容积(SV)放置在胎儿肺动脉瓣口三个不同位置(a:内侧,靠近主动脉侧;b:肺动脉瓣口中间;c:外侧,远离主动脉侧)分别获得胎儿肺动脉血流频谱,探讨不同的SV位置对胎儿肺动脉血流频谱参数的影响,从而为更准确的测量提供参考依据。方法选取424例正常胎儿,根据不同孕周分成5组,20~23+6周,24~27+6周,28~31+6周,32~35+6周,36~40+6周,分别测量其肺动脉瓣口三个位置(a、b、c)的速度时间积分(VTI)、最大血流速度(Vmax)、平均血流速度(Vmean)、最大压差(PGmax)、平均压差(PGmean)、射血时间(ET)、加速时间(AT)、加速时间与射血时间的比值(AT/ET)。不同孕周间VTI、Vmax、Vmean、PGmax、PGmean、ET、AT、AT/ET组间比较采用方差分析,各参数与孕周的关系进行Pearson相关分析,所有孕周不同取样容积位置(a、b、c)的比较采用配对t检验。结果不同孕周间VTI、Vmax、Vmean、PGmax、PGmean、AT、AT/ET组间比较差异均有统计学意义(P=0.000),且均与孕周呈线性相关,a组与b组、b组与c组比较AT、AT/ET、Vmax、Vmean有统计学意义(P=0.000),a组与c组比较AT、AT/ET、Vmax、Vmean无统计学意义(P0.05)。结论 SV位置的不同会对胎儿肺动脉血流频谱参数产生影响。
[Abstract]:Objective to obtain the flow spectrum of fetal pulmonary artery by placing SVV in three different positions of fetal pulmonary valve orifice: medial side, near the aortic side, central part of pulmonary valve, lateral side, far away from the aorta. To study the influence of different SV positions on the parameters of fetal pulmonary artery flow spectrum, and to provide reference for more accurate measurement. Methods 424 normal fetuses were divided into 5 groups according to different gestational weeks. The velocities and time integrals of the three locations of pulmonary valve orifice were measured respectively: VTI, Vmax, Vmean, PGmax, PGmeann, et, ATP, ATP / ETT, and the ratio of the acceleration time to the ejection time, to the ratio of the acceleration time to the ejection time. The variance analysis was used in the comparison of VTII VMEP VMEP VMEP Vmean PGVMEP EET ATP et group during different gestational weeks. The relationship between each parameter and gestational week was analyzed by Pearson correlation analysis. The comparison of all gestational weeks with different sampling volume locations was carried out by paired t test (P < 0.05), and the correlation between each parameter and gestational age was analyzed by Pearson correlation analysis and paired t test was used for the comparison of each parameter. Results during different gestational weeks, there were significant differences in VTII Vmean Vmean PGmaxPmax and PGmean-ATN ATP / et groups, and there was no significant difference in Vmean between group A and group B and group b and group c in comparison with group C and group C. There was no significant difference in Vmean between group A and group C. there was no significant difference between group A and group C in the Vmean value of ATT et P / P P = 0. 05% and P 0. 05%, P 0. 05%, P 0. 05%, P 0. 05% and P 0. 05% respectively, compared with group C and group C. Conclusion the difference of SV position may affect the parameters of fetal pulmonary artery flow spectrum.
【作者单位】：浙江大学医学院附属邵逸夫医院超声科浙江省胎儿心脏超声诊断技术指导中心浙江大学邵逸夫临床医学研究所;浙江省杭州市西溪医院超声科;
【基金】：浙江省医药卫生科技项目(No.2017203109)
【分类号】：R445.1;R714.5

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