选择性单胚胎移植临床结局和可行性分析

发布时间：2018-05-25 20:21

本文选题：促性腺素类 + 分裂期　；参考：《重庆医学》2017年15期

【摘要】：目的探讨行选择性单胚胎移植(eSET)的临床结局及可行性。方法回顾性分析2014年8月至2015年10月在该院生殖科进行体外受精-胚胎移植(IVF-ET)治疗的患者资料,选择行选择性移植1枚优质胚胎106个周期为eSET组,其中获卵数大于15个为高反应组(高度OHSS风险,46个周期),获卵数5~15个为正常反应组(60个周期)。移植2枚胚胎(至少1枚为优质胚胎)的106个周期为双胚胎移植组(DET)组。比较组间一般情况、促排情况、胚胎发育情况及临床妊娠率、种植率、多胎率和早期流产率。结果 eSET组Gn量和双胎妊娠率低于DET组,注射人绒毛膜促性腺激素(HCG)日雌激素(E_2)水平、获卵数、优质胚胎数和种植率均高于DET组,比较差异有统计学意义(P0.05)。高反应组注射HCG日E_2水平高于正常反应组,比较差异有统计学意义(P0.05)。结论 eSET与DET有相似的妊娠率,但能明显降低双胎妊娠率,对于特定人群应该坚持行eSET。
[Abstract]:Objective to investigate the clinical outcome and feasibility of selective single embryo transfer (eSET). Methods a retrospective analysis was made of the patients' data from August 2014 to October 2015 in the Department of reproductive department for the treatment of in vitro fertilization and embryo transfer (IVF-ET). Selective transplantation of 1 high quality embryos in 106 cycles was selected as eSET group, and the number of acquired eggs was higher than that of 15. The group (high OHSS risk, 46 cycles) and the number of acquired eggs were 5~15 as the normal reaction group (60 cycles). The 106 cycles of the transplantation of 2 embryos (at least 1 for high quality embryos) were in the double embryo transfer group (DET) group. The general situation, the condition of promoting, the embryo development and the clinical pregnancy rate, the implantation rate, the rate of multifoetus and the early abortion rate were compared, and the result was eSET. The rate of Gn and twin pregnancy was lower than that in group DET. The level of estrogen (E_2), the number of eggs obtained, the number of high quality embryos and the planting rate were higher than those in the DET group, and the difference was statistically significant (P0.05). The level of E_2 in the high reaction group was higher than that in the normal reaction group (P0.05). The difference was statistically significant (P0.05). Conclusion eSET and conclusion were statistically significant (P0.05). Conclusion eSET and conclusion were statistically significant (P0.05). Conclusion eSET and conclusion are statistically significant (P0.05). Conclusion eSET and conclusion are statistically significant (P0.05). Conclusion eSET and conclusion are statistically significant (P0.05). Conclusion eSET and conclusion are statistically significant (P0.05). Conclusion eSET and conclusion are statistically significant (P0.05). Conclusion eSET and HCG DET has similar pregnancy rate, but it can significantly reduce the rate of twin pregnancy. For specific populations, eSET. should be maintained.
【作者单位】：海南省农垦总医院生殖科;
【基金】：海南省卫生厅课题(琼卫2013自筹-20)
【分类号】：R714.8

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