妊娠期糖尿病并发症相关因素的分析

发布时间：2018-05-27 21:08

本文选题：糖尿病 + 妊娠　；参考：《中国糖尿病杂志》2015年04期

【摘要】：目的探讨GDM患者并发症的相关危险因素。方法 134例GDM患者分为无并发症组及并发症组。测定两组C-RP、FPG、FIns及血脂水平;记录母婴并发症发生情况;分析各危险因素与并发症的相关性。结果 GDM+并发症组C-RP、FPG、孕前BMI和孕晚期BMI均高于单纯GDM组[(5.46±4.20)vs(2.60±2.76)mg/L、(5.68±1.36)vs(5.25±0.77)mmol/L、(24.79±3.92)vs(23.03±2.51)kg/m2、(29.05±3.79)vs(27.25±2.58)kg/m2](P0.05)。相关分析显示,C-RP与FPG呈正相关(P0.05)。Logistic回归分析显示,孕晚期BMI、C-RP、TG和HDL-C是母体发生并发症的危险因素;C-RP是新生儿发生并发症的危险因素。结论 C-RP、血脂、孕晚期BMI与GDM母婴并发症发生密切相关;积极控制血糖、合理控制体重增加和血脂有助于减轻炎症反应,改善妊娠不良结局。
[Abstract]:Objective to investigate the risk factors of complications in patients with GDM. Methods 134 patients with GDM were divided into no complication group and complication group. The levels of FIns and blood lipids in two groups were measured, and the incidence of complications in mother and infant were recorded, and the correlation between the risk factors and complications was analyzed. Results in GDM complication group, BMI before pregnancy and BMI in late pregnancy were higher than those in GDM group [5.46 卤4.20)vs(2.60 卤2.76 mg / L, 5.68 卤1.36)vs(5.25 卤0.77 mmol / L, 24.79 卤3.92)vs(23.03 卤2.51kg / m _ 2 + 29.05 卤3.79)vs(27.25 卤2.58)kg/m2] (P < 0.05). Correlation analysis showed that C-RP was positively correlated with FPG. Logistic regression analysis showed that BMIC-RPU TG and HDL-C were the risk factors of maternal complications and C-RP was the risk factor of neonatal complications. Conclusion C-RP, blood lipids and BMI in late pregnancy are closely related to the complications of GDM, and actively controlling blood sugar, weight gain and blood lipids are helpful to alleviate inflammatory reaction and improve adverse outcome of pregnancy.
【作者单位】：首都医科大学附属北京世纪坛医院内分泌科;首都医科大学附属北京世纪坛医院产科;
【分类号】：R714.256

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