腹腔镜下卵巢子宫内膜异位囊肿剔除手术对卵巢储备功能的影响

发布时间：2018-05-28 17:45

  本文选题：卵巢子宫内膜异位症 + 囊肿剔除　； 参考：《浙江大学》2017年硕士论文

【摘要】：目的:研究腹腔镜下卵巢子宫内膜异位囊肿剔除手术对卵巢储备功能的影响。方法:选择在我院接受腹腔镜下卵巢囊肿剔除手术治疗,术后病理诊断为卵巢子宫内膜异位症的患者共212例,比较手术前后卵巢激素水平的改变来探究腹腔镜下卵巢子宫内膜异位囊肿剔除手术对卵巢储备功能的影响。结果:腹腔镜下卵巢子宫内膜异位囊肿剔除手术术后6个月内血清FSH、FSH/LH较术前明显上升,E2水平较术前明显下降(P0.05);术后6个月以上FSH/LH较术前明显上升,(P0.05),而血清FSH及E2水平较术前比较无明显变化(P0.05)。单侧卵巢子宫内膜异位囊肿手术剔除后血清FSH及FSH/LH较术前显著升高(P0.05),E2水平较术前明显下降。双侧卵巢子宫内膜异位囊肿手术剔除后血清FSH较术前差异无统计学意义(P0.05),FSH/LH较术前显著升高(P0.05),E2水平较术前明显下降(P0.05)。单侧卵巢子宫内膜异位囊肿和双侧卵巢子宫内膜异位囊肿相比较,在术前双侧卵巢囊肿FSH较单侧囊肿高(P0.05),而FSH/LH及E2水平与单侧卵巢囊肿无明显差异(P0.05)。在术后双侧卵巢囊肿FSH及E2水平与单侧卵巢囊肿无明显差异(P0.05),而FSH/LH值较单侧囊肿低(P0.05)。卵巢子宫内膜异位囊肿直径≤3cm,手术前后FSH、FSH/LH及E2水平无明显差异(P0.05)。囊肿直径3cmm且≤5cm,术后FSH及FSH/LH较术前明显升高(P0.05),E2水平无明显差异(P0.05)。囊肿直径5cm,术后FSH及FSH/LH较术前明显升高(P0.05),E2水平较术前明显下降(P0.05)。结论:腹腔镜下卵巢子宫内膜异位囊肿剔除手术可能降低卵巢的储备功能,尤其是在囊肿直径较大时,但这种影响多能在半年后恢复。
[Abstract]:Objective: to study the effect of laparoscopic ovarian endometriosis cystectomy on ovarian reserve function. Methods: a total of 212 patients with ovarian endometriosis were treated by laparoscopic ovarian cyst excision and pathologically diagnosed as ovarian endometriosis. To investigate the effect of laparoscopic ovarian endometriosis cystectomy on ovarian reserve function by comparing the changes of ovarian hormone levels before and after surgery. Results: the serum levels of FSHF / FSH / LH increased significantly within 6 months after laparoscopic ovarian endometriosis cystectomy. The level of E2 decreased significantly compared with that before operation, and the level of FSH/LH increased significantly over 6 months after operation. The serum levels of FSH and E2 were significantly higher than those before operation. There was no significant change in the level of P0.05 compared with that before operation. The levels of serum FSH and FSH/LH in patients with unilateral ovarian endometriosis were significantly higher than those before operation. There was no significant difference in serum FSH after resection of bilateral ovarian endometriosis cysts. The level of serum P0.05FSH / LH was significantly higher than that of preoperation and the level of P0.05FSH / LH was significantly lower than that of preoperation. Compared with unilateral ovarian endometriosis cysts and bilateral ovarian endometriosis cysts, the FSH of bilateral ovarian cysts was higher than that of unilateral ovarian cysts before operation, while the levels of FSH/LH and E2 were not significantly different from those of unilateral ovarian cysts. The levels of FSH and E2 in bilateral ovarian cysts were not significantly different from those in unilateral ovarian cysts (P 0.05), but the FSH/LH values were lower than those in unilateral cysts (P 0.05). The diameter of ovarian endometriosis cyst was less than 3 cm. There was no significant difference in FSH / LH and E2 levels before and after operation. The diameter of cyst 3cmm was less than 5 cm. There was no significant difference in the level of P0.05 and E2 between FSH and FSH/LH after operation. The diameter of cysts was 5 cm, and the levels of FSH and FSH/LH were significantly higher than those before operation. Conclusion: laparoscopic resection of ovarian endometriosis cysts may reduce ovarian reserve function, especially when the diameter of cyst is larger, but this effect can be recovered in half a year.
【学位授予单位】：浙江大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R713.6
，

本文编号：1947618