临产后剖宫产术后C-反应蛋白监测的临床意义

发布时间：2018-05-30 00:36

本文选题：C-反应蛋白 + 剖宫产　；参考：《中国现代医学杂志》2015年01期

【摘要】：目的探讨C-反应蛋白(CRP)在临产后剖宫产术后监测中的临床意义。方法临产后剖宫产的初产妇81例,分为发热组22例及无发热组59例。每例均于临产前、术后当天,术后第3、5、7天检测CRP水平,计算术后3~5 d及术后5~7 d CRP日均下降率。结果术前、术后当天,两组CRP无差异(P0.05)。术后第3天,两组CRP均达高峰,术后第5和7天两组CRP均有下降,在发热组均较无发热组显著升高(P0.05)。术后3~5 d发热组CRP日均下降率显著低于无发热组(P0.05)。以术后第3天CRP100 mg/L及术后3~5 d CRP日均下降率≤26.00%作为界点预测术后发热的敏感度分别为63.64%和68.75%;特异度分别为79.67%和82.76%;阳性预测值分别为53.83%和68.75%;阴性预测值分别为85.45%和82.76%。结论了解术后CRP正常变化规律,对发现、判断早期出现的感染有重要的意义。
[Abstract]:Objective to investigate the clinical significance of C-reactive protein (CRP) in postpartum cesarean section. Methods 81 cases of primipara were divided into fever group (n = 22) and non-febrile group (n = 59). The level of CRP was measured on the 3rd day of postpartum and 5th day after operation, and the average daily decline rate of CRP was calculated on the 5th day and the 57th day after the operation. Results there was no difference in CRP between the two groups before and after operation (P 0.05). On the 3rd day after operation, the CRP of both groups reached the peak, and on the 5th and 7th day after operation, the CRP of both groups decreased, and the level of CRP in the febrile group was significantly higher than that in the non-febrile group. The daily average decline rate of CRP in fever group was significantly lower than that in non-febrile group (P 0.05). The sensitivity, specificity, positive predictive value and negative predictive value were 63.64% and 68.75%, 79.67% and 82.76%, 53.83% and 68.75%, 53.83% and 68.75%, respectively. The negative predictive values were 85.45% and 82.76%, respectively. Conclusion it is important to understand the normal changes of CRP after operation and to judge the early infection.
【作者单位】：河北医科大学第一医院妇产科;
【基金】：河北省卫生厅二OO九年医学科学研究重点课题计划(No:20090335)
【分类号】：R719.8

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