围生期孕妇阴道分泌物细菌培养及耐药性分析

发布时间：2018-05-30 01:29

本文选题：围生期 + 孕妇　；参考：《中国感染控制杂志》2017年12期

【摘要】：目的了解围生期孕妇阴道病原菌分布及其药敏情况。方法对10 800例妇女(围生期孕妇和非妊娠期妇女各5 400例)阴道分泌物标本进行细菌培养及药敏试验。结果5 400例围生期孕妇病原菌检出率为26.00%(1 404株),其中真菌759株,革兰阳性球菌611株,革兰阴性杆菌32株,淋病奈瑟菌2株;5 400例非妊娠妇女病原菌检出率为7.87%(425株),其中真菌232株,革兰阳性球菌182株,革兰阴性杆菌5株,淋病奈瑟菌6株。围生期孕妇分离的无乳链球菌对红霉素、克林霉素耐药率为84.85%和80.81%,金黄色葡萄球菌对红霉素耐药率为40.91%,大肠埃希菌对四环素、复方磺胺甲口恶唑耐药率为69.23%和53.85%,淋病奈瑟菌对青霉素、复方磺胺甲口恶唑耐药率100.00%。结论围生期孕妇阴道较非妊娠育龄妇女病原菌感染率更高,加强围生期孕妇阴道病原菌的筛查力度,对保障母婴安全具有重要的临床意义。
[Abstract]:Objective to study the distribution and drug sensitivity of vaginal pathogens in pregnant women during perinatal period. Methods the bacterial culture and drug sensitivity test were performed on 10 800 samples of vaginal secretions of 10 800 women (5 400 cases of perinatal and 5 400 cases of non-pregnant women). Results the detection rate of pathogenic bacteria in 5 400 pregnant women during perinatal period was 26. 00 and 1 404 strains, including 759 fungi, 611 gram-positive cocci and 32 gram-negative bacilli, among which 759 were fungi, 611 gram-positive cocci and 32 gram-negative bacilli. The detection rate of 2 Neisseria gonorrhoeae strains in 5 400 non-pregnant women was 7.87425, including 232 fungi, 182 Gram-positive cocci, 5 Gram-negative bacilli and 6 Neisseria gonorrhoeae. The resistant rates of clindamycin to erythromycin, staphylococcus aureus and tetracycline were 84.85% and 80.81%, 40.91% and 40.91% respectively. The resistance rates of compound sulfamethoxazole were 69.23% and 53.85% respectively. The resistance rate of Neisseria gonorrhoeae to penicillin and compound sulfamethoxazole was 100.00. Conclusion the infection rate of vaginal pathogens in perinatal pregnant women is higher than that in non-pregnant women of childbearing age. It is of great clinical significance to strengthen the screening of vaginal pathogens of pregnant women during perinatal period to ensure the safety of mother and child.
【作者单位】：江西省妇幼保健院;
【基金】：江西省卫生计生委科技计划项目(20165455)
【分类号】：R446.5;R714.7

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