卵巢畸胎瘤相关抗NMDAR脑炎六例临床分析

发布时间：2018-05-31 01:44

本文选题：畸胎瘤 + 副瘤综合征　；参考：《中国妇产科临床杂志》2017年03期

【摘要】：目的探讨抗NMDAR脑炎合并卵巢肿瘤患者的临床特点,诊断标准及治疗方法。从而总结出适用于妇科医生的相关诊疗方案,提高妇科医生对该病的认识,并指导对该病的诊治,改善患者预后。方法回顾性分析2013年12月至2015年12月首都医科大学宣武医院收治的抗NMDAR脑炎合并卵巢肿瘤的6例临床资料。分析该病临床特点,诊断方案及治疗方法,并进行归纳分析。结果抗NMDAR脑炎患者临床表现特异性较差,头颅MRI等缺乏特异性,脑脊液抗NMDAR抗体检测为诊断的关键。及时诊治,预后较好。结论该病诊治难度大,作为妇科医生要充分认知该疾病,能为妇科卵巢肿瘤筛查、诊断及治疗提供重要意见,同时也能给予及时手术干预,改善预后。
[Abstract]:Objective to investigate the clinical features, diagnostic criteria and treatment of anti NMDAR encephalitis complicated with ovarian tumor. Therefore, the related diagnosis and treatment scheme for gynecologists is summarized to improve their understanding of the disease, to guide the diagnosis and treatment of the disease, and to improve the prognosis of the patients. Methods from December 2013 to December 2015, 6 cases of NMDAR encephalitis complicated with ovarian tumor were retrospectively analyzed. The clinical features, diagnosis and treatment of the disease were analyzed and summarized. Results the specificity of anti NMDAR encephalitis was poor and the MRI of head was not specific. The detection of anti NMDAR antibody in cerebrospinal fluid was the key to diagnosis. Timely diagnosis and treatment, better prognosis. Conclusion the diagnosis and treatment of the disease is very difficult. As a gynecologist, it can provide important advice for the screening, diagnosis and treatment of gynecologic ovarian tumor, and can also provide timely surgical intervention to improve the prognosis.
【作者单位】：首都医科大学宣武医院妇产科;
【分类号】：R737.31;R742.9

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