高龄不孕症患者辅助生殖技术中早期妊娠丢失的危险因素分析

发布时间：2018-06-02 20:17

本文选题：辅助生殖技术 + 高龄　；参考：《现代妇产科进展》2017年05期

【摘要】：目的:分析高龄不孕症患者接受辅助生殖技术(ART)后妊娠丢失的危险因素。方法:选择2014年1月至2016年5月于郑州大学第二附属医院生殖医学部接受ART的年龄≥35岁的不孕症患者,根据妊娠情况分为妊娠丢失组和妊娠持续组,回顾收集临床资料和实验室结果,多因素Logistic回归分析早期妊娠丢失的危险因素。结果:新鲜周期高龄不孕症患者的早期妊娠丢失率为38.81%,与年龄35岁患者比较,差异有统计学意义(P0.05)。妊娠丢失组和妊娠持续组的年龄和胚胎移植数比较,差异有统计学意义(P0.05)。Logistics回归显示,新鲜周期中年龄和胚胎移植数是危险因素。结论:对于高龄不孕症患者,提倡尽早接受ART;胚胎移植数需谨慎决定,提倡减少移植数。
[Abstract]:Objective: to analyze the risk factors of pregnancy loss in elderly patients with infertility after ART. Methods: infertile patients who received ART from January 2014 to May 2016 at the Department of Reproductive Medicine, second affiliated Hospital of Zhengzhou University were divided into two groups according to pregnancy status: the group of pregnancy loss and the group of pregnancy duration. Clinical data and laboratory results were reviewed and multivariate Logistic regression analysis was used to analyze the risk factors of early pregnancy loss. Results: the rate of early pregnancy loss was 38.81 in aged infertility patients with fresh cycle, and the difference was statistically significant compared with 35 years old patients (P 0.05). The age and the number of embryo transfer were significantly different between the group of pregnancy loss and the group of pregnancy duration. The regression analysis showed that the age and the number of embryo transfer in fresh cycle were the risk factors. Conclusion: for the elderly patients with infertility, ART should be accepted as soon as possible, and the number of embryo transfer should be determined carefully and the number of transplants should be reduced.
【作者单位】：郑州大学第二附属医院生殖医学部;
【分类号】：R714.8

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