cccPLT和NLR修正CA125预测子宫腺肌病盆腔致密粘连的临床价值

发布时间：2018-06-03 04:23

本文选题：子宫腺肌病 + 盆腔致密粘连　；参考：《中国妇产科临床杂志》2017年05期

【摘要】：目的探讨血清CA125、外周血PLT、NLR以及修正CA125预测子宫腺肌病盆腔致密粘连(pelvic dense adhesion,PDA)的临床价值。方法回顾304例腺肌病手术病例资料,采用Logistic回归分析患者CA125、PLT、NLR以及修正CA125与腺肌病PDA的相关性;使用ROC曲线评价其预测腺肌病PDA的价值。结果患者血清CA125、外周血PLT、NLR以及修正CA125与腺肌病PDA均呈正相关(P0.01或P0.05)。与单独使用血清CA125相比,修正CA125a可以提高预测腺肌病PDA的特异度(85.03%vs 83.00%)和敏感度(47.56%vs 47.47%);修正CA125b可以提高其特异度(53.13%vs 47.47%)。结论血清CA25、PLT及NLR与腺肌病患者PDA密切相关;使用PLT、NLR修正CA125能够进一步提高预测腺肌病PDA的准确性,可以为临床医师设计和实施腺肌病手术方式提供参考依据。
[Abstract]:Objective to investigate the clinical value of serum CA125, peripheral blood PLTV-NLR and modified CA125 in the prediction of pelvic compact adhesions of adenomyosis. Methods the data of 304 patients with adenomyosis were retrospectively reviewed. The correlation between CA125 and PDA of adenomyosis was analyzed by Logistic regression analysis and ROC curve was used to evaluate the value of ROC curve in predicting PDA of adenomyosis. Results there was a positive correlation between serum CA125, peripheral blood PLTV-NLR and modified CA125 and PDA of adenomyosis (P0.01 or P0.05). Compared with serum CA125 alone, modified CA125a could improve the specificity and sensitivity of PDA in predicting adenomyosis, and the sensitivity was 47.56 vs 47.470.Correction of CA125b could improve the specificity of PDA by 53.13 vs 47.47. Conclusion the serum CA25 PLT and NLR are closely related to PDA in patients with adenomyosis, and the accuracy of PDA prediction can be further improved by using PLTNLR to modify CA125, which can provide a reference for clinicians to design and perform adenomyosis surgery.
【作者单位】：安徽省蚌埠医学院;上海交通大学医学院;上海交通大学医学院附属第九人民医院;同济大学附属杨浦医院同济大学医学院妇科微创研究所;
【基金】：上海市科学技术委员会基金项目(14411972100)
【分类号】：R711.71

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