形态学低评分胚胎体外囊胚形成的相关因素及应用价值研究

发布时间：2018-06-08 10:31

本文选题：形态学低评分胚胎 + 囊胚培养　；参考：《实用妇产科杂志》2015年03期

【摘要】：在辅助生殖技术中,胚胎质量很大程度上决定了妊娠率,目前,绝大多数的辅助生殖中心主要采用形态学评分来评估胚胎的质量,在体外受精后第3天(D3)据此选择优质胚胎进行移植或冷冻保存,剩余的发育潜能低冻存意义不大的低评分胚胎多被丢弃,但随着体外培养技术的不断完善,低评分胚胎的利用得到了重新审视。已有很多文献研究报道形态学低评分胚胎的碎片程度、卵裂球数目、原核数目、卵子形态、原核期形态等是影响囊胚形成的相关因素,但其相关因素最终相关程度及依据标准各报道都有所不同,在此本文将对低形态学胚胎形成囊胚的相关因素作一综述,为临床对形态学低评分胚胎的处理提供理论依据,以更好地利用低形态学胚胎,对如何选择低形态学胚胎进行囊胚培养提供参考。
[Abstract]:In assisted reproductive technology, the quality of the embryo largely determines the pregnancy rate. At present, the majority of assisted reproductive centers mainly use morphological scores to evaluate the quality of the embryo. On the 3rd day after in vitro fertilization, high quality embryos were selected for transfer or cryopreservation. Most of the remaining embryos with low developmental potential and low score were discarded, but with the improvement of in vitro culture technology. The use of low-score embryos has been revisited. It has been reported in many literatures that the degree of fragmentation, the number of cleavage balls, the number of prokaryotes, the morphology of eggs, the morphology of prokaryotes, and so on, are related factors affecting the formation of blastocysts. However, the related factors are different in the final correlation degree and standard. In this paper, the factors related to the formation of blastocysts in low morphological embryos are reviewed in order to provide a theoretical basis for the treatment of low-grade embryos in clinic. In order to make better use of low-morphological embryos, it can be used as reference for selection of low-morphological embryos for blastocyst culture.
【作者单位】：南方医科大学南方医院;
【分类号】：R714.8

【共引文献】