胎停育相关影响因素研究

发布时间：2018-06-12 08:54

本文选题：胎停育 + 重金属　；参考：《现代预防医学》2015年02期

【摘要】：目的本研究通过分析胎停育夫妻静脉血重金属及微量元素含量以及生活、环境有关因素,探讨与胎停育发生有关的原因,为今后采取相应的预防措施、提高妇女优生优育比例奠定基础。方法选择2010年2月-2013年12月,在某院妇产科就诊或接受产前检查的孕产妇作为研究对象,将临床检查及B超辅助诊断确诊为胚胎停止发育、自然流产的夫妻84对作为观察组;将同时期在该院接受产检至分娩且新生儿无异常的夫妻84对作为对照组。采用原子吸收分光光度计法检测患者静脉血中锌、铜、铅的元素的含量,并采用自行设计的问卷比较2组差异。结果女性观察组与对照组比较,血锌的含量差异有统计学意义,观察组血锌水平低于对照组(t=17.18,P0.01)。血铅水平有差异,观察组血铅水平高于对照组(t=15.74,P0.01)。结论女性孕期血液中微量元素及配偶血液中重金属水平与胎停育的发生具有相关性,应加强孕前宣传,普及孕前检查及孕前医学咨询,避免接触有害因素,从而提高优生优育的比例。
[Abstract]:Objective by analyzing the contents of heavy metals and trace elements in venous blood of couples with fetal arrest and the factors related to life and environment, this study explored the causes related to the occurrence of fetal arrest, and took corresponding preventive measures in the future. We will lay the foundation for increasing the proportion of women who have good children and have better children. Methods from February 2010 to December 2013, the pregnant and lying-in women in a hospital were selected as the study objects. 84 couples with spontaneous abortion and 84 couples with spontaneous abortion were diagnosed as the observation group by clinical examination and B-ultrasound assisted diagnosis. 84 couples with no abnormal newborns in the same period were used as control group. The contents of zinc, copper and lead in venous blood of patients were determined by atomic absorption spectrophotometer, and the differences between the two groups were compared by self-designed questionnaire. Results compared with the control group, the serum zinc level in the observation group was significantly lower than that in the control group, and the serum zinc level in the observation group was lower than that in the control group. The level of blood lead in the observation group was higher than that in the control group. Conclusion the levels of trace elements in the blood of pregnant women and heavy metals in the blood of their spouses are correlated with the occurrence of fetal arrest. It is necessary to strengthen prepregnancy propaganda, popularize pre-pregnancy examination and pre-pregnancy medical consultation, and avoid exposure to harmful factors. So as to increase the proportion of eugenics and good children.
【作者单位】：湖北省中山医院妇产科;湖北省中山医院超声科;湖北省中山医院肝病科;
【分类号】：R714.5

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