情感障碍与患者围产期、胎儿期高危因素的相关性研究

发布时间：2018-06-14 11:43

本文选题：情感障碍 + 产科并发症　；参考：《青岛大学》2014年硕士论文

【摘要】：目的：通过将情感障碍和非情感障碍患者接触到胎儿期和围产期高危因素进行比较,探讨情感障碍与患者胎儿期、围产期高危因素的相关性。方法：回顾2012.09～2013.12在山东省青州荣军医院精神科住院的情感障碍患者,全部病例由本专业主治医师以上资历医生给予明确诊断,诊断符合中国疾病分类方法与诊断标准第三版的修订版情感性精神障碍的诊断标准(CCMD3)。将其与来自我院其他科室同期住院的非精神障碍患者进行对照。由经过专业培训的人员核对资料,并按统一标准整理后,采取双人双机录入资料。使用Excel2003建立数据库,采用SPSS17.0软件进行统计分析。以a=0.05为检验水准。对单因素分析中有统计学意义的危险因素带入Logistic回归模型,用向后法逐步筛选变量。P0.05为有统计学意义。结果：两组患者在母孕期精神状况、母孕期接触有毒物质、母孕期感冒史、母孕期并发症、母生产期并发症、新生儿期并发症、家族史等方面,差异有统计学意义(P0.05)。而母孕期感冒史、母生产期并发症、阳性家族史是情感障碍患者患病的的高危因素(P0.05)。讨论：本研究应用了规范的病例对照研究方法,研究组与对照组在应答率、性别、居住地、受教育程度、母孕年龄各因素无统计学差异(P0.05),说明病例组与对照组有很好的可比性。本研究显示,母孕期感冒史、母生产期并发症、阳性家族史是情感障碍患者患病的的高危因素。结论情感障碍患者组较对照组的产科并发症的发生率高,情感障碍与患者围产期、胎儿期高危因素有密切相关性,注重优生优育对控制情感障碍疾病的发生具有重要意义。
[Abstract]:Objective: to explore the relationship between affective disorder and perinatal risk factors by comparing the high risk factors of fetal and perinatal period in patients with affective disorder and non-affective disorder. Methods: the patients with affective disorder in Department of Psychiatry, Qingzhou Rongjun Hospital, Shandong Province, were retrospectively reviewed. The diagnostic criteria for affective disorders in accordance with the third edition of the Chinese Classification of Diseases and Diagnostic Standards are CCMD3. It was compared with non-mental disorder patients who were hospitalized in other departments of our hospital at the same time. By the professional training personnel check the data, and according to the unified standards, double-machine data entry. Using Excel 2003 to establish the database, SPSS 17.0 software for statistical analysis. Take A0. 05 as the test level. The risk factors with statistical significance in univariate analysis were brought into Logistic regression model, and the stepwise screening of variables (.P0.05) was statistically significant. Results: there were significant differences between the two groups in maternal mental status, maternal exposure to toxic substances, maternal cold history, maternal pregnancy complications, maternal birth complications, neonatal complications, family history and so on. Maternal cold history, maternal birth complications and positive family history were high risk factors for affective disorder patients (P 0.05). Discussion: the standard case-control study method was used in this study. The response rate, sex, place of residence, education level of the study group and the control group were studied. There was no significant difference in maternal pregnancy age between the two groups (P 0.05), which indicated that there was good comparability between the case group and the control group. This study showed that maternal pregnancy cold history, maternal birth complications, positive family history are high risk factors for affective disorder patients. Conclusion the incidence of obstetric complications in the affective disorder group is higher than that in the control group, and affective disorder is closely related to perinatal and fetal risk factors. It is of great significance to pay attention to eugenics and eugenics to control the occurrence of affective disorders.
【学位授予单位】：青岛大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R714.2

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