蔗糖铁静脉注射治疗晚期妊娠中度缺铁性贫血效果观察

发布时间：2018-06-20 08:19

本文选题：妊娠并发症 + 晚期妊娠　；参考：《山东医药》2017年34期

【摘要】：目的观察蔗糖铁静脉注射治疗晚期妊娠中度缺铁性贫血的临床疗效。方法将96例晚期妊娠中度贫血患者随机分为两组各48例,观察组静脉注射蔗糖铁,对照组口服复方硫酸亚铁叶酸片,治疗4周。治疗前后取静脉血检测血红蛋白(Hb)、红细胞压积(Hct)、血清铁蛋白(SF)、血清转铁蛋白饱和度(TSAT)及肝肾功能,记录治疗期间不良反应情况。结果两组治疗前外周血Hb、Hct、SF、TSAT水平比较,P均0.05;两组治疗后外周血Hb、Hct、SF、TSAT水平较治疗前升高,且观察组治疗后外周血Hb、Hct、SF、TSAT水平高于对照组(P均0.05)。治疗前后,两组肝肾功能均正常。治疗期间观察组出现瘙痒1例,对照组出现恶心2例、腹泻1例,临床症状轻微未影响妊娠,两组不良反应比较差异无统计学意义。结论蔗糖铁静脉注射治疗晚期妊娠中度贫血安全有效。
[Abstract]:Objective to observe the clinical effect of sucrose iron intravenous injection in the treatment of moderate iron deficiency anemia in late pregnancy. Methods Ninety-six patients with moderate anemia in late pregnancy were randomly divided into two groups: 48 patients in each group were treated with sucrose iron intravenously and the control group were treated with compound folic acid sulfate tablets for 4 weeks. Before and after treatment, the levels of HB, HCT, SFD, TSAT and liver and kidney function were measured, and the adverse reactions were recorded. Results the levels of TSAT in peripheral blood of the two groups before and after treatment were both 0.05, and the TSAT levels of hbhctttir hcttit in the two groups were higher than those before treatment, and the TSAT levels of hbhctttir in the observation group were higher than those in the control group after treatment (P = 0.05, P = 0.05, respectively), and there was no significant difference between the treatment group and the control group (P > 0.05). Before and after treatment, both liver and kidney function were normal. There were 1 case of pruritus in the observation group, 2 cases of nausea and 1 case of diarrhea in the control group during the treatment period. The clinical symptoms did not affect pregnancy slightly. There was no significant difference in adverse reactions between the two groups. Conclusion sucrose iron intravenous injection is safe and effective in the treatment of moderate anemia in late pregnancy.
【作者单位】：淮安市妇幼保健院;
【分类号】：R714.254

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