剖宫产妇运用抗菌药物预防感染的临床研究

发布时间：2018-06-20 16:25

本文选题：用药时机 + 头孢菌素类　；参考：《中华医院感染学杂志》2017年07期

【摘要】：目的探讨剖宫产妇预防感染的合理应用抗菌药物方法,为产妇临床用药提供科学参考依据。方法选择2015年6月-2016年1月4家三级甲等医院行腹膜内剖宫产妇100例,其中择期剖宫产组50例及急诊剖宫产组50例,每组根据头孢菌素类药物使用时间分为结扎前用药组和结扎后用药组,回顾性分析不同用药时机的产妇术后感染情况。结果在择期剖宫产病例中,脐带结扎前用药组的术后第一天最高体温,术后三天平均体温及术后体温恢复正常所需时间均显著低于脐带结扎后用药组(P0.05),100例剖宫产10例发生感染,感染率为10.00%;在择期及非择期剖宫产病例中,脐带结扎前用药组的感染率显著低于脐带结扎后用药组(P0.05),在所有剖宫产病例中,抗菌药物产生的费用,脐带结扎前用药组低于脐带结扎后用药组(P0.05)。结论择期或急症剖宫产产妇脐带结扎前使用抗菌药物优于脐带结扎后,可以有效降低术后感染的发生,并减轻患者的经济负担。
[Abstract]:Objective to explore the rational application of antimicrobial drugs in preventing infection in cesarean section women and to provide scientific reference for clinical use of drugs. Methods 100 cases of intraperitoneal cesarean section were performed in 4 Grade 3A hospitals from June 2015 to January 2016, including 50 cases in elective cesarean section group and 50 cases in emergency caesarean section group. Each group was divided into two groups according to the time of use of cephalosporins before and after ligation. Results in the elective cesarean section, the highest body temperature on the first day, the average body temperature on the third day and the time required for the recovery of postoperative body temperature were significantly lower than that in the group of 100 cases of cesarean section after umbilical cord ligation, and 10 cases of cesarean section in the group of preligation of umbilical cord were infected. The infection rate was 10.00. The infection rate before umbilical cord ligation was significantly lower in caesarean section group than that in post-umbilical cord ligation group (P 0.05). In all cesarean section cases, the cost of antimicrobial agents was significantly lower than that in umbilical cord ligation group. Before umbilical cord ligation, the drug group was lower than that after umbilical cord ligation group (P 0.05). Conclusion Antimicrobial agents before umbilical cord ligation in elective or emergency cesarean section are better than those after umbilical cord ligation, which can effectively reduce the incidence of postoperative infection and reduce the economic burden of the patients.
【作者单位】：安徽医科大学第二附属医院妇产科;皖北煤电集团总医院妇产科;
【基金】：国家自然科学基金青年科学基金资助项目(81100412)
【分类号】：R719.8

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