预防性输卵管切除术对卵巢功能的影响及其对盆腔疾病的预防作用

发布时间：2018-06-20 19:57

本文选题：卵巢肿瘤 + 预防性输卵管切除术　；参考：《吉林大学学报(医学版)》2017年03期

【摘要】：目的:探讨围绝经期女性因子宫良性疾病行开腹全子宫切除术同时预防性切除双侧输卵管对卵巢功能的影响以及对盆腔疾病(卵巢恶性肿瘤、卵巢良性肿瘤和盆腔炎性疾病等)的预防作用。方法:选择因子宫良性疾病行开腹全子宫切除术的患者100例,其中仅行全子宫切除术者50例作为对照组,行全子宫切除术同时行预防性双侧输卵管切除术者50例作为预防组。比较2组患者手术时间、术中出血量、排气时间和住院时间;比较术前及术后6个月、术后1年患者的卵巢基础窦卵泡数目和血清雌二醇(E2)、卵泡刺激素(FSH)及黄体生成素(LH)水平以及围绝经期综合征的发生率,随访患者术后盆腔疾病的发生率。结果:2组患者手术时间、术中出血量、排气时间及住院时间比较差异无统计学意义(P0.05);与术前比较,2组患者术后6个月和术后1年卵巢基础窦卵泡数目减少,E2水平降低,FSH和LH水平升高(P0.01);但组间卵巢基础窦卵泡数目和E2、FSH及LH水平比较差异无统计学意义(P0.05)。2组患者术后围绝经期综合征发生率比较差异无统计学意义(P0.05)。2组患者术后6个月、术后1年卵巢恶性肿瘤和卵巢良性肿瘤发病率比较差异无统计学意义(P0.05);对照组患者术后盆腔炎性疾病发病率明显高于预防组(P0.05)。对照组有2例患者术后确诊为输卵管癌,预防组有2例患者输卵管病理回报见不典型细胞。结论:切除子宫同时行预防性输卵管切除术对患者卵巢功能未见明显影响,且能够有效降低盆腔良、恶性疾病及盆腔炎性疾病的发病率。
[Abstract]:Objective: To explore the preventive effect of bilateral fallopian tubes on ovarian function and the prevention of pelvic diseases (ovarian malignant tumor, benign ovarian tumor and pelvic inflammatory disease) in perimenopausal women with benign uterine diseases. 100 cases were treated with total hysterectomy in 50 cases as control group. Total hysterectomy and 50 cases of prophylactic bilateral salpingectomy were taken as prevention group. The operation time, intraoperative bleeding, exhaust time and hospitalization time were compared in the 2 groups, and the ovarian basal sinus eggs were compared before and 6 months after operation and 1 years after operation. The number of vesicles and serum estradiol (E2), follicular stimulating hormone (FSH) and luteinizing hormone (LH), and the incidence of perimenopausal syndrome. The incidence of postoperative pelvic diseases was followed up. Results: there was no significant difference between the 2 groups of operation time, intraoperative bleeding, exhaust time and time of hospitalization (P0.05); compared with preoperative, 2 groups were affected. 6 months after operation and 1 years after operation, the number of ovarian basal sinus follicles decreased, E2 level decreased, and the level of FSH and LH increased (P0.01), but there was no significant difference in the number of ovarian basal sinus follicles with E2, FSH and LH levels (P0.05) there was no significant difference in the incidence of perimenopausal syndrome after operation (P0.05).2 group. In the last 6 months, there was no significant difference in the incidence of malignant ovarian tumor and benign ovarian tumor in 1 years after operation (P0.05); the incidence of postoperative pelvic inflammatory disease in the control group was significantly higher than that in the prevention group (P0.05). In the control group, 2 patients were diagnosed as fallopian tube cancer after operation, and 2 cases of the tubal pathological return in the prevention group were atypical cells. Theory: hysterectomy and prophylactic salpingectomy on ovarian function in patients with no obvious effect, and can effectively reduce the pelvic benign, malignant disease and pelvic inflammatory disease.
【作者单位】：吉林大学中日联谊医院妇产科;
【基金】：吉林省卫计委科研基金资助课题(20152034) 吉林省科技厅国际合作项目资助课题(20170414033GH)
【分类号】：R713.5

【相似文献】