活血化瘀方联合米非司酮治疗子宫肌瘤88例

发布时间：2018-06-23 13:38

本文选题：米非司酮 + 活血化瘀　；参考：《南京中医药大学学报》2015年04期

【摘要】：目的观察活血化瘀方联合米非司酮治疗子宫肌瘤的临床疗效。方法 174例采用药物保守治疗的子宫肌瘤患者随机分为研究组和对照组,对照组(86例)给予米非司酮,研究组(88例)额外给予自拟活血化瘀方,疗程3月。比较2组子宫和肌瘤体积、临床症状、临床疗效、孕激素(P)的改变。结果与治疗前比,2组子宫体和肌瘤的体积均明显缩小(P0.05),研究组与对照组比,P0.05。研究组白带增多、月经异常、经期腹痛的有效率都明显高于对照组,差异均具有统计学意义(P0.05)。研究组总有效率为96.59%(85/88),明显高于对照组的81.40%(70/86),差异具有统计学意义(P0.05)。2组治疗后的P水平明显下降,与治疗前比较差异均具有统计学意义(P0.05),研究组优于对照组(P0.05)。结论活血化瘀方联合米非司酮治疗子宫肌瘤能更明显提高临床疗效、改善临床症状、缩小肌瘤体积,并且对孕激素的抑制作用更为显著。
[Abstract]:Objective to observe the clinical effect of Huoxue Huayu decoction combined with mifepristone in treating uterine leiomyoma. Methods 174 patients with uterine leiomyoma treated with drug conservative therapy were randomly divided into two groups: the control group (n = 86) and the control group (n = 86). The study group (n = 88) was treated with self-made Huoxue Huayu recipe for 3 months. The changes of uterine and myoma volume, clinical symptoms, clinical efficacy and progesterone (P) were compared between the two groups. Results compared with before treatment, the volume of uterine body and leiomyoma in the two groups were significantly reduced (P0.05), and that in the study group and control group was higher than that in the control group (P 0.05). The effective rate of leucorrhea, abnormal menstruation and abdominal pain in the study group was significantly higher than that in the control group (P0.05). The total effective rate of the study group was 96.59% (85 / 88), which was significantly higher than that of the control group (81.40%) (70 / 86). The difference was statistically significant (P0.05). Conclusion Huoxue Huayu decoction combined with mifepristone in the treatment of uterine leiomyoma can significantly improve the clinical efficacy, improve clinical symptoms, reduce the volume of myoma, and the inhibitory effect of progesterone is more significant.
【作者单位】：枣庄矿业集团枣庄医院妇产科;枣庄矿业集团中心医院东郊分院妇产科;
【分类号】：R737.33

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