子宫动脉血流值在子痫前期中的预测价值

发布时间：2018-06-26 20:43

本文选题：子痫前期 + 预测　；参考：《上海交通大学学报(医学版)》2015年02期

【摘要】：目的探讨子宫动脉血流值在子痫前期中的预测价值。方法选取2012年4月—2013年6月1 630例孕妇,分别于孕11~14周及孕22~24周时采用多普勒彩色超声诊断仪检测其双侧子宫动脉收缩期与舒张期流速比(S/D)、搏动指数(PI)、阻力指数(RI)和血流频谱中的舒张早期切迹等4项指标,并随访至产后,按照妊娠结局分为发生子痫前期和对照组。先分别以S/D、PI和RI作为检验变量作ROC曲线,通过统计学检验比较预测结果,取约登指数最大者作为各单项指标的预测界值,再以各单项指标的预测界值作为评分标准建立综合评分,并采用此方法进行子痫前期的预测研究,确定其预测分值并评价其预测效果。结果1 630例孕妇中1 482例未发生子痫前期,52例发生子痫前期,另外96例为妊娠期高血压,孕22~24周时其S/D、PI及RI的预测界值分别为2.355 0、0.877 5及0.580 0。分别将S/D值、PI值和RI值这3项单项指标作为子痫前期的预测方法均具有显著的统计学意义(P0.01)。以综合评分指数3分作为预测界值预测子痫前期具有统计学意义(P=0.012),其预测特异性为97.33%。且此评分方法预测结果与新生儿出生体质量及出生孕周均呈负相关。结论运用子宫动脉血流指标用于预测子痫前期,具有很好的临床应用价值。
[Abstract]:Objective to study the predictive value of uterine artery blood flow in preeclampsia. Methods from April 2012 to June 2013, 1 630 pregnant women were selected. At 1114 weeks and 2224 weeks of gestation, the systolic and diastolic velocity ratio (S / D), pulsatility index (Pi), resistance index (RI) and early diastolic notch of bilateral uterine arteries were measured by color Doppler ultrasound. Follow-up to postpartum, according to pregnancy outcome divided into preeclampsia and control group. The ROC curves were made by using S / DX Pi and RI as test variables respectively. The results were compared by statistical test. The largest of Jorden index was taken as the prediction bound value of each single index. Then the prediction threshold of each single index is taken as the scoring standard to establish the comprehensive score. The prediction of preeclampsia is studied by using this method to determine the prediction score and evaluate the effect of the pre-eclampsia prediction. Results among 1 630 pregnant women, 1 482 cases had no preeclampsia and 52 cases had preeclampsia, the other 96 cases were gestational hypertension. The predicted values of S- / DNPI and RI were 2.355 and 0.580 respectively at the 24th week of gestation. There was significant statistical significance in using the three single indexes of S / D and RI as preeclampsia prediction methods (P0.01). It was statistically significant to predict preeclampsia with a comprehensive score index of 3 (P0. 012), and the predictive specificity was 97. 33%. The predicted results were negatively correlated with birth weight and gestational age. Conclusion the application of uterine artery blood flow index to predict preeclampsia has good clinical value.
【作者单位】：上海交通大学医学院附属国际和平妇幼保健院妇产科;上海交通大学医学院附属国际和平妇幼保健院超声科;
【基金】：上海市卫生局基金(20114146)~~
【分类号】：R714.244

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