妇科肿瘤患者术后泌尿系统感染的相关因素及耐药性分析

发布时间：2018-06-27 03:28

本文选题：泌尿系感染 + 相关因素　；参考：《中华医院感染学杂志》2017年24期

【摘要】：目的探讨妇科肿瘤术后泌尿系感染的危险因素、病原菌及耐药性,为临床预防及治疗妇科肿瘤术后泌尿系感染提供依据。方法选取2014年3月-2016年12月医院妇科肿瘤患者912例,收集患者年龄、肿瘤类型等临床资料,观察分析泌尿系感染病原学检测结果与药物敏感性检测结果等。结果妇科肿瘤患者术后泌尿系感染120例,感染率为13.16%;多因素logistic回归分析结果显示,年龄、术后住院时间、合并糖尿病、留置导尿时间为术后泌尿系感染的影响因素(P0.05);120例术后泌尿系感染患者共培养出163株病原菌,其中革兰阳性菌44株占26.99%,革兰阴性菌104株占63.80%,真菌15株占9.20%;大肠埃希菌对氨苄西林、头孢噻肟、头孢他啶、头孢吡肟的耐药率较高,肠球菌属对磺胺甲VA唑/甲氧苄啶、阿莫西林/克拉维酸钾、红霉素、四环素、庆大霉素的耐药率较高。结论妇科肿瘤术后泌尿系感染发生与高龄、手术时间长、术后住院时间长、合并糖尿病及留置导尿时间长相关;感染以革兰阴性菌为主;细菌对氨苄西林、头孢类耐药率较高,对亚胺培南、美罗培南耐药率较低。
[Abstract]:Objective to explore the risk factors, pathogens and drug resistance of urinary tract infection after gynecological tumor operation, and to provide evidence for clinical prevention and treatment of urinary tract infection after gynecological tumor operation. Methods from March 2014 to December 2016, 912 patients with gynecological tumors were collected and their age, tumor type and other clinical data were collected, and the results of etiology and drug sensitivity of urinary tract infection were observed and analyzed. Results 120 cases of postoperative urinary tract infection were found in patients with gynecological neoplasms, the infection rate was 13.16.The results of multivariate logistic regression analysis showed that age, postoperative hospitalization time, diabetes mellitus, The time of indwelling catheterization was the influencing factor of urinary tract infection after operation (P0.05) 163 strains of pathogenic bacteria were cultured in 120 cases of postoperative urinary tract infection, among which 44 strains of Gram-positive bacteria accounted for 26.99%, 104 strains of Gram-negative bacteria accounted for 63.80 strains, 15 strains of fungi accounted for 9.20%, Escherichia coli for ampicillin, The resistant rates of cefotaxime, ceftazidime and cefepime were higher. The resistance rates of Enterococcus to sulfamethazol / trimethoprim, amoxicillin / clavulanate potassium, erythromycin, tetracycline and gentamicin were higher. Conclusion the incidence of urinary tract infection after operation of gynecological tumor is related to the age, the operation time is long, the hospital stay time is long, the complications of diabetes mellitus and indwelling urethral catheterization are long, the infection is mainly Gram-negative bacteria, the rate of bacterial drug resistance to ampicillin and cefazolin is higher. The resistance to imipenem and meropenem was low.
【作者单位】：郑州大学第二附属医院妇科;
【分类号】：R691.3;R737.3

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