血浆置换在产后HELLP综合征治疗中的作用

发布时间：2018-06-28 05:18

本文选题：HELLP综合征 + 血浆置换　；参考：《重庆医学》2017年34期

【摘要】：目的探讨血浆置换对产后HELLP综合征的临床治疗效果。方法选取2014年1月至2015年12月,该院收治的44例产后HELLP综合征患者作为治疗组,在常规治疗的基础上联合应用血浆置换;同时选取该院2012年1月至2013年12月收治的47例产后HELLP综合征患者作为对照组,进行常规治疗。在治疗前、治疗后检测血红蛋白(Hb)、血小板(PLT)、凝血酶原时间(PT)、血清天门冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)、血清总胆红素(TBIL)、结合胆红素(DBIL)、血清乳酸脱氢酶(LDH)、血尿素氮(BUN)、肌酐(Cr)水平变化情况;同时比较两组患者住ICU时间,PLT、ALT、AST和LDH恢复时间。结果治疗后,治疗组患者PLT、AST、ALT、LDH的水平与对照组比较,差异有统计学意义(P0.05);治疗组患者住ICU时间,PLT、ALT、AST和LDH的恢复时间均低于对照组(P0.05)。结论血浆置换可以明显改善产后HELLP综合征患者的临床症状,提高治愈率。
[Abstract]:Objective to investigate the effect of plasma exchange on postpartum HELLP syndrome. Methods 44 patients with postpartum HELLP syndrome treated in our hospital from January 2014 to December 2015 were selected as treatment group. Plasma exchange was combined with plasma exchange on the basis of routine treatment. 47 cases of postpartum HELLP syndrome treated in our hospital from January 2012 to December 2013 were selected as control group. Before treatment, After treatment, hemoglobin (HB), platelet (PLT), prothrombin time (PT), serum aspartate aminotransferase (AST), alanine aminotransferase (alt), total bilirubin (TBIL), conjugated bilirubin (DBIL), serum lactate dehydrogenase (LDH), blood urea nitrogen (bun) were measured. Anhydride (Cr) level change; The time of stay in ICU and the recovery time of alt AST and LDH in the two groups were compared at the same time. Results after treatment, the level of LDH in the treatment group was significantly higher than that in the control group (P0.05), and the recovery time of AST and LDH in the treatment group was lower than that in the control group (P0.05). Conclusion Plasma exchange can significantly improve the clinical symptoms and cure rate of postpartum HELLP syndrome.
【作者单位】：天津市第三中心医院妇产科;
【分类号】：R714.246

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