219例多囊卵巢综合征临床分析
发布时间:2018-07-03 02:48
本文选题:多囊卵巢综合征 + 肥胖 ; 参考:《安徽医科大学学报》2015年04期
【摘要】:目的探讨多囊卵巢综合征(PCOS)患者的临床特点和发病机制。方法收集219例符合2003年鹿特丹诊断标准的PCOS患者,同时选取63例正常者作为对照组(N组);将PCOS患者分为两组:体重正常的PCOS患者为LP组,超重或肥胖的PCOS患者为NLP组。采集病史,进行体格检查;测定性激素及血糖、血脂等各项生化指标,进行口服糖耐量试验;最后对数据进行统计学分析。结果 1 219例PCOS患者里存在胰岛素抵抗(IR)患者[胰岛素抵抗指数(HOMA-IR)≥2.69]144例(66.36%)。2 NLP组空腹、餐后胰岛素水平升高,与N组相比差异有统计学意义(P0.01);3 LP组促黄体生成素(LH)、睾酮(T)与N组相比增高,差异有统计学意义(P0.05,P0.01)。结论 IR不是PCOS发病的单纯因素,卵巢功能异常亦需关注。
[Abstract]:Objective to investigate the clinical features and pathogenesis of polycystic ovary syndrome (PCOS). Methods 219 PCOS patients who met the Rotterdam diagnostic criteria in 2003 and 63 normal subjects as control group were divided into two groups: LP group with normal body weight and NLP group with overweight or obese PCOS patients. Collection of medical history, physical examination; determination of sex hormones, blood sugar, blood lipid and other biochemical indicators, oral glucose tolerance test; finally, statistical analysis of the data. Results in 1,219 PCOS patients with insulin resistance (IR) [HOMA-IR 鈮,
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