宫颈癌患者放疗过程中靶区体积及位移变化

发布时间：2018-07-09 19:45

本文选题：宫颈癌 + 放射治疗　；参考：《广东医学》2015年16期

【摘要】：目的探讨宫颈癌患者放疗过程中靶区体积、位置的改变。方法选择20例行宫颈癌放疗的患者,比较放疗前与放疗中期GTV、膀胱和直肠体积,以及三者边界在左、右、腹、背、头和脚6个方向上的位置变化。结果与放疗前相比,放疗中期20例患者GTV体积均缩小,差异有统计学意义(P0.05);膀胱和直肠体积变化差异无统计学意义(P0.05);放疗中与放疗前GTV、膀胱、直肠的体积比≥70%,三者的空间重复体积比≤50%。GTV在左、右、头侧位移最大,膀胱在头、脚、腹侧位移最大,直肠在头、脚、背侧位移最大;放疗前与放疗中三者在6个方向上的位移差异有统计学意义(P0.05)。结论宫颈癌患者放疗过程中膀胱、直肠体积均有变化,但无规律可言,加之靶区及正常组织的移动,放疗中期重新计划或自适应放疗是必要的。
[Abstract]:Objective to investigate the changes in the volume and position of the target area in the radiotherapy of cervical cancer patients. Methods 20 patients with cervical cancer were selected to compare the GTV, the volume of the bladder and rectum before and after radiotherapy, and the changes in the position of the three boundary in the left, right, abdominal, back, head and foot in the 6 directions of the three. The volume of the bladder and rectum was not statistically significant (P0.05), and the volume of bladder and rectum had no significant difference (P0.05). The volume ratio of bladder and rectum was more than 70% in radiotherapy and before radiotherapy. The spatial repetition volume ratio of the three had the largest left, right, head side displacement, the largest displacement of the bladder in the head, foot and ventral side, and the head, foot, and dorsal displacement of the rectum. The difference between the three in 6 directions was statistically significant (P0.05). Conclusion the volume of bladder and rectum in the radiotherapy of cervical cancer patients has changed, but there is no law, and the movement of target area and normal tissue, it is necessary to replan or adapt to adaptive radiotherapy in the target area and normal tissue.
【作者单位】：广州医科大学附属肿瘤医院放疗中心;
【基金】：广东省教育厅特色创新项目(自然科学类)(编号:2014KTSCX104) 广州市医药卫生科技项目(编号:20131A011165)
【分类号】：R737.33

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