Ets-1在子宫内膜癌中的表达及意义

发布时间：2018-07-10 12:12

本文选题：子宫内膜癌 + Ets-　；参考：《现代妇产科进展》2017年06期

【摘要】：目的:探讨Ets-1在子宫内膜癌组织中的表达及其与临床分期、病理分级、分型及预后的关系。方法:免疫组化SP法检测子宫内膜癌及正常子宫内膜组织中Ets-1表达,荧光原位杂交法检测Ets-1 mRNA表达。结果:子宫内膜癌组织中Ets-1蛋白阳性表达率为88.8%,高于正常子宫内膜。子宫内膜癌组织中Ets-1表达与临床病理分期、肌层浸润与病理分级有关,差异有统计学意义(P0.05)。结论:Ets-1与子宫内膜癌的临床分期、病理分级、转移密切相关。
[Abstract]:Objective: To investigate the expression of Ets-1 in endometrial carcinoma and its relationship with clinical stage, pathological classification, classification and prognosis. Methods: immunohistochemical SP method was used to detect the expression of Ets-1 in endometrial carcinoma and normal endometrium, and the expression of Ets-1 mRNA was detected by fluorescence in situ hybridization. Results: the positive expression of Ets-1 protein in endometrial carcinoma tissue was expressed. The rate was 88.8%, higher than that of normal endometrium. Ets-1 expression in endometrial carcinoma and clinicopathological stages, myometrium infiltration and pathological grading were associated with statistical significance (P0.05). Conclusion: Ets-1 is closely related to the clinical staging, pathological classification and metastasis of endometrial carcinoma.
【作者单位】：山东省临沂市中心医院妇科;
【基金】：山东省卫生厅基金(No:2014WS0290)
【分类号】：R737.33

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