宫颈上皮内瘤变锥切术后复发的相关预测因素

发布时间：2018-07-11 10:37

  本文选题：宫颈上皮内瘤变 + 高危型人乳头瘤病毒　； 参考：《实用医学杂志》2015年04期

【摘要】：目的:探讨高危型人乳头瘤病毒(HR-HPV)检测在宫颈锥切术(Cold Knife Conization,CKC)术后随访的临床应用价值。方法:将行宫颈锥形切除术的205例患者为随访对象,根据病理结果分为2组:未累腺组(92例)及累腺组(113例),对其手术前后的HPV感染变化情况进行观察及分析。结果:两组患者术后HPV转阴率相比差异无统计学意义(P0.05);是否累及腺体及HPV负荷量是CKC术后残存病变或复发的危险因素(P0.05);HPV负荷量1 000的宫颈锥切术后患者的残存病变或复发的危险性是HPV负荷量≤500的7.286倍。结论:累腺患者术后残存病变或复发的危险性更高;HPV负荷量越高,术后残存病变或复发的机率越大;HPV检测能帮助预测CIN宫颈锥切术后的复发率。
[Abstract]:Objective: to evaluate the clinical value of high risk human papillomavirus (HR-HPV) detection in the follow-up of cervical conization (Cold Knife conization CKC). Methods: 205 cases of cervical conical resection were followed up. According to the pathological results, 205 patients were divided into two groups: unaffected gland group (92 cases) and involved gland group (113 cases). The changes of HPV infection before and after operation were observed and analyzed. Results: there was no significant difference in HPV negative rate between the two groups (P0.05), and the risk factor of residual lesion or recurrence after CKC was whether the HPV load was involved or not (P0.05). The risk of change or recurrence was 7.286 times greater than that of HPV load 鈮，

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