体外受精-胚胎移植过程中焦虑抑郁、子宫收缩频率和妊娠结局的相关性
发布时间：2018-07-17 22:01
【摘要】：目的探讨体外受精-胚胎移植(IVF/ICSI)过程中移植日焦虑抑郁与妊娠结局的关系、子宫收缩频率与妊娠结局的关系、焦虑抑郁与子宫收缩频率的关系。方法选取2014-01~2014-07符合标准的86例行IVF/ISCI治疗的不孕症患者作为研究对象,于胚胎移植日,发放焦虑自评量表(SAS)及抑郁自评量表(SDS)的调查问卷,现场调查现场收回。同时阴道超声监测患者子宫收缩波,并记录。观察妊娠结局至胚胎移植后4周,按妊娠结局分为临床妊娠组和非妊娠组,分析焦虑抑郁、子宫收缩频率与妊娠结局的相关性。结果临床妊娠组39例,非妊娠组47例。移植日非妊娠组的SAS评分明显高于临床妊娠组(P0.05),而两组SDS评分比较,差异无统计学意义(P0.05)。移植日的SAS评分与妊娠结局进行回归分析,SAS评分与妊娠结局相关(P0.05),SAS评分越低,成功妊娠可能性越大;两组不同妊娠结局间的子宫收缩频率比较,临床妊娠组子宫收缩频率≤4次/min较非妊娠组多(P0.05),移植日子宫收缩频率与妊娠结局相关(P0.05),子宫收缩频率过强不容易妊娠;将移植日的SAS评分与子宫收缩频率进行关联性分析,移植日的子宫收缩频率与SAS评分之间有正相关性(r=0.704,P0.05)。结论对于接受IVF/ICSI治疗的不孕症患者,移植日子宫收缩频率过快及明显焦虑的患者,不容易妊娠,且焦虑情绪可能导致子宫收缩频率增加,不利于妊娠。
[Abstract]:Objective to investigate the relationship between anxiety depression and pregnancy outcome during in vitro fertilization and embryo transfer (IVF / ICSI), the relationship between uterine contraction frequency and pregnancy outcome, and the relationship between anxiety depression and uterine contraction frequency. Methods 86 infertile patients who were treated with IVF / ISCI from 2014-01 to 2014-07 were selected as study objects. Self-Rating anxiety scale (SAS) and Self-Rating Depression scale (SDS) were distributed on the day of embryo transfer. At the same time, vaginal ultrasound monitored the uterine contractions in patients and recorded them. The pregnancy outcome was observed from 4 weeks after embryo transfer and divided into clinical pregnancy group and non-pregnancy group according to pregnancy outcome. The relationship between anxiety and depression uterine contraction frequency and pregnancy outcome was analyzed. Results 39 cases in clinical pregnancy group and 47 cases in non-pregnancy group. The SAS score of non-pregnancy group was significantly higher than that of clinical pregnancy group (P0.05), but there was no significant difference in SDS score between the two groups (P0.05). Regression analysis was carried out between SAS score and pregnancy outcome on the transplantation day. (P0.05) the lower the SAS score was, the greater the possibility of successful pregnancy; the frequency of uterine contraction was compared between the two groups with different pregnancy outcomes. The frequency of uterine contraction in clinical pregnancy group 鈮，
本文编号：2131063
[Abstract]:Objective to investigate the relationship between anxiety depression and pregnancy outcome during in vitro fertilization and embryo transfer (IVF / ICSI), the relationship between uterine contraction frequency and pregnancy outcome, and the relationship between anxiety depression and uterine contraction frequency. Methods 86 infertile patients who were treated with IVF / ISCI from 2014-01 to 2014-07 were selected as study objects. Self-Rating anxiety scale (SAS) and Self-Rating Depression scale (SDS) were distributed on the day of embryo transfer. At the same time, vaginal ultrasound monitored the uterine contractions in patients and recorded them. The pregnancy outcome was observed from 4 weeks after embryo transfer and divided into clinical pregnancy group and non-pregnancy group according to pregnancy outcome. The relationship between anxiety and depression uterine contraction frequency and pregnancy outcome was analyzed. Results 39 cases in clinical pregnancy group and 47 cases in non-pregnancy group. The SAS score of non-pregnancy group was significantly higher than that of clinical pregnancy group (P0.05), but there was no significant difference in SDS score between the two groups (P0.05). Regression analysis was carried out between SAS score and pregnancy outcome on the transplantation day. (P0.05) the lower the SAS score was, the greater the possibility of successful pregnancy; the frequency of uterine contraction was compared between the two groups with different pregnancy outcomes. The frequency of uterine contraction in clinical pregnancy group 鈮，
本文编号：2131063
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