加味八珍汤联合催产素对足月妊娠孕妇宫颈成熟影响的临床研究

发布时间：2018-07-24 21:09

【摘要】：通过对辨证为气血虚弱型的足月妊娠孕妇选用加味八珍汤口服,联合应用催产素的观察,初步探讨加味八珍汤联合催产素对于促进妊娠足月孕妇宫颈成熟的作用。本研究采用随机对照的试验方法,将符合纳入标准的研究对象180例,随机分为治疗组即加味八珍汤联合催产素组60例,对照组即催产素组60例,空白组即期待观察组60例。观察用药前后各组宫颈成熟度评分(Bishop评分)、阴道和宫颈分泌物胎儿纤连蛋白(FFN)定性检测结果、分娩结局及对母胎的影响。结果表明,治疗组孕妇宫颈评分在用药后明显优于对照组、空白组(P0.05)。FFN测定在治疗组用药后与对照组、空白组间差异有统计学意义(P0.05)。3组孕妇用药后治疗组临产率、阴道分娩率均高于其他2组,差异有统计学意义(P0.05)。治疗组剖宫产率明显低于其他2组,差异有统计学意义(P0.05)。3组均未出现新生儿窒息的现象。加味八珍汤联合催产素能有效地促宫颈成熟和引产,使用方便、安全可靠,对母儿无明显不良影响,在降低剖宫产率,促进自然分娩上起到积极作用。
[Abstract]:The effect of Jiawei Bazhen decoction combined with oxytocin on cervix maturation of pregnant women with term pregnancy was preliminarily discussed through oral administration of Jiawei Bazhen decoction and observation of oxytocin. 180 subjects were randomly divided into treatment group (n = 60), control group (n = 60) and blank group (n = 60). The cervical maturity score (Bishop score), fetal fibronectin (FFN) of vaginal and cervical secretions, the outcome of delivery and the effect on maternal and fetal were observed before and after treatment. The results showed that the cervical score of pregnant women in the treatment group was significantly better than that in the control group after medication, the blank group (P0.05) .FFN measurement after the treatment group and the control group, there was significant difference between the blank group (P0.05). Vaginal delivery rate was higher than the other two groups, the difference was statistically significant (P0.05). The rate of cesarean section in the treatment group was significantly lower than that in the other two groups, and the difference was statistically significant (P0.05). Jiawei Bazhen decoction combined with oxytocin can effectively promote cervix maturation and induced labor. It is easy to use, safe and reliable, has no obvious adverse effect on mother and baby, and plays a positive role in reducing cesarean section rate and promoting natural delivery.
【作者单位】：广州中医药大学第一附属医院;
【基金】：广东省中医药局基金项目(20131175)
【分类号】：R719.31

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