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达英-35联合二甲双胍对青春期多囊卵巢综合征卵巢功能的影响

发布时间:2018-08-31 14:49
【摘要】:目的探讨青春期多囊卵巢综合征患者接受二甲双胍+达英-35联合治疗对其卵巢功能的影响。方法选取青春期多囊卵巢综合征患者76例为研究对象,按照抽签分为对照组和试验组各38例,分别行单纯性达英-35疗法、二甲双胍+达英-35联合疗法,对比两组疗效。结果试验组治疗有效率94.74%较对照组68.42%高,E2(106.32±20.8)pmol/L、T(1.62±0.51)mmol/L、LH(8.60±2.63)U/L较对照组的(120.35±21.23)pmol/L、(2.14±1.12)mmol/L、(14.95±3.75)U/L低,LH/FSH(10.32±2.24)、FSH(10.32±2.23)U/L较对照组的(8.83±2.06)、(8.85±2.03)U/L高,且胰岛素抵抗(1.25±0.46)较对照组(2.57±0.61)明显下降,差异均有统计学意义(P0.05)。结论对青春期多囊卵巢综合征患者行二甲双胍+达英-35联合治疗疗效确切,能有效调节其卵巢功能,改善胰岛素抵抗,值得临床积极借鉴。
[Abstract]:Objective to investigate the effect of metformin-35 on ovarian function in adolescent patients with polycystic ovary syndrome (PCOS). Methods 76 cases of pubertal polycystic ovary syndrome were divided into two groups according to drawing lots, 38 cases in control group and 38 cases in test group. They were treated with simple diane-35 and metformin 35 respectively, and the curative effect was compared between the two groups. 缁撴灉璇曢獙缁勬不鐤楁湁鏁堢巼94.74%杈冨鐓х粍68.42%楂,

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