72例卵巢交界性肿瘤临床分析
发布时间:2018-09-04 15:00
【摘要】:目的:分析卵巢交界性肿瘤(BOT)患者的临床特征、手术方式及预后等情况,以指导临床医生对不同患者选择最佳治疗方案。方法:对2012年1月1日至2015年12月31日期间蚌医一附院的卵巢交界性肿瘤患者行回顾性分析。比较其临床特点、病理类型、辅助检查、临床分期、手术方式及术后治疗情况,并分析其预后。所有病例信息来源于我院病案室、病理科及彩超室。结果:共有72例患者纳入分析。其年龄中位数为44岁(范围18~85岁),平均年龄45.21±16.19岁。大多数的患者(84.7%)表现为国际妇产科联盟(FIGO)分期I期,其余为FIGO分期II/III期(II期4.2%,III期11.1%)。这些患者中,浆液性肿瘤占58.3%,粘液性为37.5%,其余为子宫内膜样和混合型。其中血清癌抗原125(CA125)水平升高发生于54.2%的患者中。所有患者均接受手术治疗,行保留生育功能的手术者占44.4%,根治性手术者为55.6%(40/72),有3例患者行双附件+大网膜切除术,归为根治性手术。Ⅰ期患者行保留生育功能手术的复发率显著高于根治性手术者(P0.05)。肿瘤剥除比患侧附件切除者更容易复发。所有患者有6.9%行辅助化疗。术后随访10~55月,仅1例出现肿瘤相关性死亡,11.1%出现复发。复发后部分行手术治疗,其中有1例局部癌变。结论:BOT预后良好,临床表现无明显特异性,手术是其主要治疗方法。育龄期有生殖意愿的患者可行保留生育功能的手术,Ⅰ期者建议行患侧附件切除术。对于行保留生育功能手术的患者应行长期密切随访。无生育要求者建议行根治性手术。术后辅助化疗对BOT的作用不大,不建议行辅助化疗。
[Abstract]:Objective: to analyze the clinical features, surgical methods and prognosis of (BOT) patients with borderline ovarian tumors, so as to guide clinicians to choose the best treatment for different patients. Methods: the patients with borderline ovarian tumors from January 1, 2012 to December 31, 2015 were retrospectively analyzed. The clinical features, pathological types, adjuvant examinations, clinical stages, surgical procedures and postoperative treatment were compared and their prognosis was analyzed. All cases were collected from the medical records room, pathology department and color Doppler room of our hospital. Results: a total of 72 patients were included in the analysis. The median age was 44 years (range 18 to 85 years), with an average age of 45.21 卤16.19 years. The majority of the patients (84.7%) showed stage I of (FIGO) in the International Federation of Obstetrics and Gynaecology, and the rest of the patients were in II/III stage of FIGO stage (II 4.2%, stage III 11.1%). Of these patients, serous tumors accounted for 58.3 percent, mucus 37.5 and endometrioid and mixed. The serum CA125 level increased in 54.2% of the patients. All the patients received surgical treatment. 44.4% of the patients underwent surgery and 55.6% (40 / 72) of the patients underwent radical surgery. Three patients underwent double adnexal omentectomy. The recurrence rate of stage 鈪,
本文编号:2222508
[Abstract]:Objective: to analyze the clinical features, surgical methods and prognosis of (BOT) patients with borderline ovarian tumors, so as to guide clinicians to choose the best treatment for different patients. Methods: the patients with borderline ovarian tumors from January 1, 2012 to December 31, 2015 were retrospectively analyzed. The clinical features, pathological types, adjuvant examinations, clinical stages, surgical procedures and postoperative treatment were compared and their prognosis was analyzed. All cases were collected from the medical records room, pathology department and color Doppler room of our hospital. Results: a total of 72 patients were included in the analysis. The median age was 44 years (range 18 to 85 years), with an average age of 45.21 卤16.19 years. The majority of the patients (84.7%) showed stage I of (FIGO) in the International Federation of Obstetrics and Gynaecology, and the rest of the patients were in II/III stage of FIGO stage (II 4.2%, stage III 11.1%). Of these patients, serous tumors accounted for 58.3 percent, mucus 37.5 and endometrioid and mixed. The serum CA125 level increased in 54.2% of the patients. All the patients received surgical treatment. 44.4% of the patients underwent surgery and 55.6% (40 / 72) of the patients underwent radical surgery. Three patients underwent double adnexal omentectomy. The recurrence rate of stage 鈪,
本文编号:2222508
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