重度子痫前期病情发展与衍变396例分析
发布时间：2018-09-09 17:37
【摘要】：目的探讨重度子痫前期(sPE)患者病情的发展与衍变,寻求减少疾病发生、延缓病情发展及避免严重并发症和不良结局的临床要点。方法分析2009年1月至2012年12月于北京大学第三医院住院治疗并终止妊娠、在出院时诊断为重度子痫前期的396例患者资料,按入院情况进行分组,包括入院时为单纯sPE不伴有严重并发症(I-sPE)组330例;sPE伴有严重并发症(C-sPE)组33例;轻度子痫前期(mild preeclampsia)后发展为sPE(M-sPE)组23例;入院时无子痫前期诊断但住院后发展成为sPE(N-sPE)组10例。分析指标包括一般临床资料、产前检查情况及病情衍变分析。结果 (1)M-sPE组规律产检率最高(87%),C-sPE组规律产检率最低(50%)。重症首诊患者中,C-sPE组比例(63.6%)高于I-sPE组(44.2%)(P0.05)。(2)C-sPE组首发征象出现最早,入院孕周较晚;M-sPE组诊断sPE孕周较晚,分娩孕周均值大于34孕周,无一例出现严重并发症。(3)N-sPE组10例均存在≥1个的预警信息;8例接受了常规性的规律产前检查;7例临床首发征象出现在入院前;入院至sPE诊断中位时间8.0(5.0,16.0)d;sPE诊断至分娩中位时间2.5(0.8,8.5)d。结论重度子痫前期可以经不同发病情形衍变而来,注重临床预警信息是早期识别重度子痫前期发病的重要环节之一,在存在子痫前期高危因素的孕妇尤其在期待治疗过程中应早期识别、注意防范重度子痫前期发生;产前检查和管理质量是影响重度子痫前期发病的重要因素。
[Abstract]:Objective to investigate the development and evolution of (sPE) patients with severe preeclampsia, and to explore the clinical key points to reduce the occurrence of the disease, delay the development of the disease and avoid serious complications and adverse outcomes. Methods from January 2009 to December 2012, the data of 396 patients with severe preeclampsia diagnosed as severe preeclampsia were analyzed. There were 33 cases of sPE with severe complications (C-sPE), 23 cases of sPE (M-sPE) after mild pre-eclampsia (mild preeclampsia), 10 cases of sPE (N-sPE) group with no pre-eclampsia diagnosis at admission. The analysis included general clinical data, prenatal examination and disease evolution analysis. Results (1) M-sPE group had the highest regular rate (87%) and C-sPE group had the lowest regular rate (50%). The proportion of patients with severe first visit in C-sPE group (63.6%) was higher than that in I-sPE group (44.2%) (P0.05). (2). The initial sign of sPE was the earliest in the C-sPE group. The diagnosis of sPE in M-sPE group was later than that in M-sPE group, and the mean gestational week of delivery was more than 34 weeks. No serious complications occurred. (3) in the N-sPE group, 10 cases had 鈮，
本文编号：2233098
[Abstract]:Objective to investigate the development and evolution of (sPE) patients with severe preeclampsia, and to explore the clinical key points to reduce the occurrence of the disease, delay the development of the disease and avoid serious complications and adverse outcomes. Methods from January 2009 to December 2012, the data of 396 patients with severe preeclampsia diagnosed as severe preeclampsia were analyzed. There were 33 cases of sPE with severe complications (C-sPE), 23 cases of sPE (M-sPE) after mild pre-eclampsia (mild preeclampsia), 10 cases of sPE (N-sPE) group with no pre-eclampsia diagnosis at admission. The analysis included general clinical data, prenatal examination and disease evolution analysis. Results (1) M-sPE group had the highest regular rate (87%) and C-sPE group had the lowest regular rate (50%). The proportion of patients with severe first visit in C-sPE group (63.6%) was higher than that in I-sPE group (44.2%) (P0.05). (2). The initial sign of sPE was the earliest in the C-sPE group. The diagnosis of sPE in M-sPE group was later than that in M-sPE group, and the mean gestational week of delivery was more than 34 weeks. No serious complications occurred. (3) in the N-sPE group, 10 cases had 鈮，
本文编号：2233098
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