活血抑异方对气滞血瘀型盆腔子宫内膜异位症术后复发率的影响

发布时间：2018-09-12 19:43

【摘要】：目的:研究活血抑异方对气滞血瘀型盆腔子宫内膜异位症术后复发率的影响。方法:选取我院2013年2月至2015年2月74例盆腔子宫内膜异位症患者为研究对象,所有患者均行开腹或腹腔镜保守型手术。将纳入患者按随机数表法分为观察组与对照组,每组37例。对照组给予常规西医治疗,观察组给予自拟活血抑异方治疗,比较两组血液流变学指标、免疫功能、血管生成因子、性激素、复发率、妊娠率、不良反应。结果:观察组1年复发率、2年复发率分别为2.7%、8.1%,显著低于对照组的16.2%、27.0%。观察组治疗3个月后血浆粘度比、免疫球蛋白A(IgA)、免疫球蛋白G(IgG)、内皮生长因子(VEGF)、血管生成素-2(Ang-2)分别优于对照组。结论:自拟活血抑异方可以通过改变患者血液流变性,改善机体免疫机能,调节血管生成因子,预防子宫内膜异位症术后复发。
[Abstract]:Objective: to study the effect of Huoxue Yi Fang on recurrence rate of pelvic endometriosis with Qi stagnation and Blood stasis. Methods: 74 patients with pelvic endometriosis from February 2013 to February 2015 were selected. All patients underwent open or laparoscopic conservative surgery. The patients were divided into observation group (n = 37) and control group (n = 37). The control group was treated with routine western medicine, and the observation group was treated with self-made Huoxue Yi decoction. The hemorheology index, immune function, angiogenesis factor, sex hormone, recurrence rate, pregnancy rate and adverse reaction were compared between the two groups. Results: the recurrence rates of 1 year and 2 years in the observation group were 2. 7% and 8. 1 respectively, which were significantly lower than that in the control group (16. 2%) and 27. 0% in the control group. The plasma viscosity ratio and immunoglobulin A (IgA), immunoglobulin G (IgG), endothelial growth factor (VEGF), angiopoietin -2 (Ang-2) in the observation group were higher than those in the control group after 3 months of treatment. Conclusion: the self-made prescription of activating blood circulation and Yi can prevent the recurrence of endometriosis after operation by changing the hemorheology, improving the immune function and regulating the angiogenesis factor.
【作者单位】：南阳理工学院张仲景国医学院;
【分类号】：R711.71

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