超排卵全程应用225U促黄体生成素对取卵及胚胎移植日血清血管内皮生长因子水平的影响

发布时间：2018-09-14 16:03

【摘要】：【目的】探讨促黄体生成素在控制性超排卵中降低血清血管内皮生长因子水平的有效性。【方法】20例在超排卵全程添加225 U促黄体生成素(实验组)同50例未添加患者(对照组)比较超排卵启动日血清血管内皮生长因子水平,人绒毛膜激素注射日、取卵日及胚胎移植日血清血管内皮生长因子较启动日的升高水平。【结果】试验组及对照组启动日血清血管内皮生长因子水平及人绒毛膜激素注射日血清血管内皮生长因子较启动日的升高水平差异不具有统计学意义;试验组取卵日(P=0.017)及胚胎移植日血清血管内皮生长因子较启动日的升高水平(P=0.009)同对照组相比,差异具有统计学意义。【结论】225 U促黄体生成素在超排卵全程应用可有效降低取卵及胚胎移植日血清血管内皮生长因子水平。
[Abstract]:[objective] to investigate the efficacy of luteinizing hormone (LPO) in reducing the level of serum vascular endothelial growth factor (VEGF) during controlled hyperovulation. [methods] Twenty patients were treated with 225U luteinizing hormone (experimental group) in the whole process of hyperovulation, and 50 patients were not treated with luteinizing hormone. The serum levels of vascular endothelial growth factor (VEGF) on the day of superovulation were compared with those in the control group. Human chorionic hormone injection day, The level of serum vascular endothelial growth factor (VEGF) on the day of egg extraction and embryo transfer was higher than that on the start day. [results] the level of serum vascular endothelial growth factor (VEGF) in the test group and the control group on the start day and the day of human chorionic hormone injection was higher than that on the start day. There was no significant difference in the elevated level of skin growth factor compared with that on the start day. The serum levels of vascular endothelial growth factor (VEGF) on the day of egg collection (P0. 017) and on the day of embryo transfer were higher than those of the control group (P0. 009). [conclusion] 225U luteinizing hormone can effectively reduce the level of serum vascular endothelial growth factor (VEGF) on the day of oocyte collection and embryo transfer.
【作者单位】：中山大学附属第一医院生殖医学中心//广东省生殖医学重点实验室;
【基金】：广州市科技计划项目(201300000097) 广东省生殖医学站实验室建设项目(2012A061400003)
【分类号】：R714.8

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