淋巴细胞免疫治疗不明原因复发性流产不同疗程临床效果分析

发布时间：2018-09-16 21:43

【摘要】：目的探讨本院生殖门诊患者淋巴细胞主动免疫治疗对原因不明性复发性流产不同疗程的疗效。方法选取本院患者200例,治疗组:提取其丈夫淋巴细胞进行主动免疫,孕前及孕后均4次。对照组:同样进行淋巴细胞主动免疫,孕前4次,孕后只注射1~2次。自孕前免疫治疗4次疗程完成时开始,18个月后对其封闭抗体转阳率、妊娠成功率等进行比较。结果 2组比较对照组封闭抗体转阳率、妊娠成功率均低于治疗组,差异有统计学意义(P0.05)。结论淋巴细胞提取治疗免疫原因引起的复发性流产,微创,操作简单,安全经济,疗效满意,值得临床推广。
[Abstract]:Objective to investigate the effect of lymphocyte active immunotherapy on different courses of unexplained recurrent abortion. Methods 200 patients in our hospital were selected, the treatment group: the husband lymphocytes were extracted for active immunization, 4 times before pregnancy and 4 times after pregnancy. Control group: the same lymphocyte active immunization, 4 times before pregnancy, only 1 injection 2 times after pregnancy. At the end of 4 courses of immunotherapy before pregnancy, the positive rate of blocking antibody and the success rate of pregnancy were compared after 18 months. Results the positive rate of blocking antibody and the success rate of pregnancy in the two groups were lower than those in the treatment group, the difference was statistically significant (P0.05). Conclusion Lymphocyte extraction in the treatment of recurrent abortion caused by immune causes, minimally invasive, simple operation, safe and economical, satisfactory curative effect, worthy of clinical promotion.
【作者单位】：河北省衡水市第二人民医院;
【分类号】：R714.21

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