不同的胚胎移植管对体外受精-胚胎移植技术结局的影响
发布时间：2018-09-17 14:08
【摘要】：目的:比较不同的胚胎移植管对新鲜体外受精-胚胎移植技术(in vitro fertilization-embryo transfer,IVF-ET)妊娠结局的影响。方法:自2012年7月至2013年11月,由同一移植医生完成前瞻性对照研究,选取在北京大学第三医院生殖医学中心完成IVF-ET/卵胞浆内单精子注射(intracytoplasmic sperm injection,ICSI)-ET治疗的2 064个新鲜胚胎移植周期,分为两组,组1采用Cook Sydney IVF移植管(型号:K-JETS-7019-SIVF)移植,共949周期,组2采用Frydman~汶CCD管(型号:131230301)移植,共1 115周期,比较不同的移植管对IVF结局的影响。结果:在年龄、不孕原因、促排卵方案、平均获卵数、平均移植胚胎数及胚胎评价等基本情况一致的情况下,组1的着床率、临床妊娠率及活产率均显著高于组2(34.40%vs.26.92%,51.21%vs.41.52%,42.57%vs.33.09%,P值均0.05),两组流产率差异没有统计学意义(11.93%vs.15.98%,P0.05),组1的困难移植比例高于组2(5.27%vs.3.41%,P0.05),两组困难移植周期的临床妊娠率及活产率无显著差异。结论:不同移植管可能会影响IVF结局,COOK Sydney IVF移植管可获得较好的临床妊娠结果。
[Abstract]:Aim: to compare the effects of different embryo transfer tubes on the pregnancy outcome of fresh IVF-embryo transfer technique (in vitro fertilization-embryo transfer,IVF-ET). Methods: from July 2012 to November 2013, a prospective controlled study was conducted by the same transplant doctor. A total of 2 064 fresh embryos were treated with intracytoplasmic sperm injection of IVF-ET/ (intracytoplasmic sperm injection,ICSI) -ET at the Reproductive Medicine Center of Peking University third Hospital, and were divided into two groups. Group 1 was transplanted with a Cook Sydney IVF transfer tube (type 1: K-JETS-7019-SIVF) for a total of 949 cycles. Group 2 was transplanted with Frydman~ Wen CCD tube (No. 1: 131230301) for 1 115 cycles. The effect of different graft tubes on the outcome of IVF was compared. Results: the implantation rate of group 1 was consistent with age, cause of infertility, ovulation promotion program, average number of eggs acquired, average number of embryos transferred and embryo evaluation. The clinical pregnancy rate and live delivery rate were significantly higher in group 2 than in group 2 (34.40vs.26.92and 51.21vs.41.52v s.42.57vs.33.09mg). There was no significant difference in abortion rate between the two groups (11.93vs.15.98p0.05). The proportion of difficult transplantation in group 1 was higher than that in group 2 (5.27vs.3.41P0.05). There was no significant difference in clinical pregnancy rate and live birth rate between the two groups. Conclusion: different grafts may influence the outcome of IVF.
【作者单位】： 北京大学第三医院生殖医学中心;
【基金】：国家自然科学基金(81501325)资助~~
【分类号】：R714.8
本文编号：2246172
[Abstract]:Aim: to compare the effects of different embryo transfer tubes on the pregnancy outcome of fresh IVF-embryo transfer technique (in vitro fertilization-embryo transfer,IVF-ET). Methods: from July 2012 to November 2013, a prospective controlled study was conducted by the same transplant doctor. A total of 2 064 fresh embryos were treated with intracytoplasmic sperm injection of IVF-ET/ (intracytoplasmic sperm injection,ICSI) -ET at the Reproductive Medicine Center of Peking University third Hospital, and were divided into two groups. Group 1 was transplanted with a Cook Sydney IVF transfer tube (type 1: K-JETS-7019-SIVF) for a total of 949 cycles. Group 2 was transplanted with Frydman~ Wen CCD tube (No. 1: 131230301) for 1 115 cycles. The effect of different graft tubes on the outcome of IVF was compared. Results: the implantation rate of group 1 was consistent with age, cause of infertility, ovulation promotion program, average number of eggs acquired, average number of embryos transferred and embryo evaluation. The clinical pregnancy rate and live delivery rate were significantly higher in group 2 than in group 2 (34.40vs.26.92and 51.21vs.41.52v s.42.57vs.33.09mg). There was no significant difference in abortion rate between the two groups (11.93vs.15.98p0.05). The proportion of difficult transplantation in group 1 was higher than that in group 2 (5.27vs.3.41P0.05). There was no significant difference in clinical pregnancy rate and live birth rate between the two groups. Conclusion: different grafts may influence the outcome of IVF.
【作者单位】： 北京大学第三医院生殖医学中心;
【基金】：国家自然科学基金(81501325)资助~~
【分类号】：R714.8
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