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克罗米芬单用或联合尿促性素对不同直径卵泡妊娠的影响

发布时间:2018-10-09 17:16
【摘要】:目的探讨克罗米芬(CC)单用与CC联合尿促性素(HMG)两种促排卵方案中不同直径卵泡的临床妊娠情况。方法采用回顾性病例对照研究,选取行宫腔内人工授精治疗的143例患者共242个周期,采用CC单用或CC联合HMG促排卵治疗,比较两组间临床妊娠率及流产率,进一步将两种促排卵方案中妊娠患者按人绒毛膜促性腺激素(HCG)日卵泡直径分为3组(15~17 mm组、18~20 mm组、≥21 mm组),分析不同直径卵泡妊娠患者构成比及流产率。结果两种促排卵方案中,周期妊娠率与流产率差异无统计学意义(P0.05)。但两组中HCG日主导卵泡直径为18~20 mm组妊娠患者所占比例高于主导卵泡直径为15~17 mm组及主导卵泡直径≥21 mm组,且差异有统计学意义(P0.05),3组间流产率均差异无统计学意义(P0.05)。结论 CC单用或CC联合HMG促排卵治疗时宜在主导卵泡直径为18~20 mm时注射HCG。
[Abstract]:Objective to investigate the clinical status of follicles with different diameters in ovulation promotion regimen of clomiphene (CC) alone and CC combined with urotropin (HMG). Methods A retrospective case-control study was conducted in 143 patients with intrauterine artificial insemination for 242 cycles. Ovulation was treated with CC alone or CC combined with HMG. The clinical pregnancy rate and abortion rate were compared between the two groups. According to the diameters of human chorionic gonadotropin (HCG) day follicles, the pregnant women were further divided into three groups according to the day follicle diameter of human chorionic gonadotropin (HCG) (1517 mm group, 1820 mm group, 鈮,

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