硝酸甘油治疗妊娠高血压的临床疗效

发布时间：2018-10-29 17:54

【摘要】：目的探讨硝酸甘油治疗妊娠高血压的临床疗效。方法选取枣阳市妇幼保健院2014年1月—2017年1月收治的妊娠高血压患者90例,随机分为对照组和试验组,各45例。对照组患者采用硫酸镁治疗,观察组患者给予硝酸甘油治疗。比较两组患者临床疗效及治疗前后平均动脉压、24 h尿蛋白含量,并观察患者不良反应发生情况。结果观察组患者临床疗效优于对照组(P0.05)。治疗前,两组患者平均动脉压和24 h尿蛋白含量比较,差异无统计学意义(P0.05);治疗后,观察组患者平均动脉压和24 h尿蛋白含量低于对照组(P0.05)。观察组患者不良反应发生率低于对照组(P0.05)。结论采用硝酸甘油治疗妊娠高血压的临床疗效确切,可有效降低患者血压及24h尿蛋白含量,且安全性好。
[Abstract]:Objective to investigate the clinical effect of nitroglycerin in the treatment of pregnancy-induced hypertension. Methods from January 2014 to January 2017, 90 patients with pregnancy-induced hypertension in Zaoyang Maternal and Child Health Hospital were randomly divided into control group and experimental group, each with 45 cases. The patients in the control group were treated with magnesium sulfate, and the patients in the observation group were treated with nitroglycerin. The clinical efficacy, mean arterial pressure and 24 h urinary protein content before and after treatment were compared between the two groups, and adverse reactions were observed. Results the clinical effect of the observation group was better than that of the control group (P0.05). Before treatment, there was no significant difference in mean arterial pressure and 24 h urinary protein content between the two groups (P0.05); after treatment, the mean arterial pressure and 24 h urinary protein content in the observation group were lower than those in the control group (P0.05). The incidence of adverse reactions in the observation group was lower than that in the control group (P0.05). Conclusion nitroglycerin is effective in the treatment of pregnancy-induced hypertension. It can effectively reduce blood pressure and 24 hours urine protein content, and is safe.
【作者单位】：湖北省枣阳市妇幼保健院;
【分类号】：R714.246

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