地塞米松治疗重度妊娠高血压合并血小板减少综合征疗效观察

发布时间：2018-11-05 21:05

【摘要】：目的:探究地塞米松治疗重度妊娠高血压合并血小板减少综合征的临床治疗效果。方法:选择120例重度妊娠高血压合并血小板减少综合征孕妇,分为对照组和观察组各60例,观察组根据孕妇的血小板计数情况给予分组,其中轻度组18例,中度组20例,重度组22例。对所有孕妇采用解痉挛以及镇静、降压、扩容、利尿等治疗措施,对照组采用硫酸镁治疗,观察组给予地塞米松治疗,最后对所有孕妇的临床表现以及预后情况进行比较分析。结果:观察组的并发症以及围产儿死亡情况与对照组相比差异有统计学意义(P0.05),且重度组孕妇的妊娠并发症以及围产儿死亡率高于中度组与轻度组(P0.05);在产妇预后中,轻度组的ALT、肝功能以及血小板恢复时间优于中度组与重度组(P0.05)。结论:采用地塞米松对重度妊娠高血压合并血小板减少综合征孕妇进行治疗,适时终止妊娠,能够有效降低并发症与围产儿死亡率,改善母婴预后,可以在临床医学中得以广泛地推广应用。
[Abstract]:Objective: to investigate the clinical effect of dexamethasone in the treatment of severe pregnancy-induced hypertension complicated with thrombocytopenia syndrome. Methods: 120 pregnant women with severe pregnancy-induced hypertension complicated with thrombocytopenia syndrome were divided into two groups: control group (n = 60) and observation group (n = 60). Severe group 22 cases. All pregnant women were treated with antispasticity, sedation, hypotension, dilatation, diuretic therapy, the control group was treated with magnesium sulfate, the observation group was treated with dexamethasone, and the clinical manifestations and prognosis of all pregnant women were compared and analyzed. Results: the complications and perinatal mortality in the observation group were significantly higher than those in the control group (P0.05), and the pregnancy complications and perinatal mortality in the severe group were higher than those in the moderate group and the mild group (P0.05). In maternal prognosis, ALT, liver function and platelet recovery time in mild group were better than those in moderate group and severe group (P0.05). Conclusion: using dexamethasone to treat pregnant women with severe pregnancy-induced hypertension and thrombocytopenia syndrome and terminating pregnancy timely can effectively reduce complications and perinatal mortality and improve the prognosis of mother and infant. It can be widely used in clinical medicine.
【作者单位】：山西省妇幼保健院;
【分类号】：R714.2

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